P0CG47: Polyubiquitin-B

General Information

Protein names	- Polyubiquitin-B - Ubiquitin
Gene names	UBB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P0CG47

10 N-termini

9 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN
        70         80         90        100        110        120
IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVEPSDTIE NVKAKIQDKE GIPPDQQRLI
       130        140        150        160        170        180
FAGKQLEDGR TLSDYNIQKE STLHLVLRLR GGMQIFVKTL TGKTITLEVE PSDTIENVKA
       190        200        210        220
KIQDKEGIPP DQQRLIFAGK QLEDGRTLSD YNIQKESTLH LVLRLRGGC

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 9 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P0CG47-1-unknown	MQIFVK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P0CG47-1-	MQIFVK...	1			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P0CG47-55-acetylation	TLSDYN...	55	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P0CG47-65-acetylation	STLHLV...	65	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P0CG47-73-unknown	LRGGMQ...	73		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15762
P0CG47-75-unknown	GGMQIF...	75		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15763
P0CG47-77-unknown	MQIFVK...	77		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P0CG47-149-unknown	LRGGMQ...	149		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15764
P0CG47-151-unknown	GGMQIF...	151		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15765
P0CG47-153-unknown	MQIFVK...	153		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HLVLRL	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15762
...VLRLRG	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15763
...RLRGGM	76	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HLVLRL	148	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15764
...VLRLRG	150	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15765
...RLRGGM	152	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HLVLRL	224	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15766
...VLRLRG	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15767
...RLRGGC	228	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
IDE_HUMAN	72	VLRL.\|.LRGG	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,
IDE_HUMAN	74	RLRG.\|.GGMQ	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,
IDE_HUMAN	148	VLRL.\|.LRGG	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,
IDE_HUMAN	150	RLRG.\|.GGMQ	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,
IDE_HUMAN	224	VLRL.\|.LRGG	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,
IDE_HUMAN	226	RLRG.\|.GGC	inferred from experiment	unknown	MEROPS	Tang WJ	Ralat LA et al.:Ubiquitin is a novel substrate ... (M16.002)	21185309,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)