TopFIND 4.0

P10630: Eukaryotic initiation factor 4A-II

General Information

Protein names
- Eukaryotic initiation factor 4A-II
- eIF-4A-II
- eIF4A-II
- 3.6.4.13
- ATP-dependent RNA helicase eIF4A-2
Gene names Eif4a2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P10630

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA YGFEKPSAIQ 
        70         80         90        100        110        120 
QRAIIPCIKG YDVIAQAQSG TGKTATFAIS ILQQLEIEFK ETQALVLAPT RELAQQIQKV 
       130        140        150        160        170        180 
ILALGDYMGA TCHACIGGTN VRNEMQKLQA EAPHIVVGTP GRVFDMLNRR YLSPKWIKMF 
       190        200        210        220        230        240 
VLDEADEMLS RGFKDQIYEI FQKLNTSIQV VLLSATMPTD VLEVTKKFMR DPIRILVKKE 
       250        260        270        280        290        300 
ELTLEGIKQF YINVEREEWK LDTLCDLYET LTITQAVIFL NTRRKVDWLT EKMHARDFTV 
       310        320        330        340        350        360 
SALHGDMDQK ERDVIMREFR SGSSRVLITT DLLARGIDVQ QVSLVINYDL PTNRENYIHR 
       370        380        390        400    
IGRGGRFGRK GVAINFVTEE DKRILRDIET FYNTTVEEMP MNVADLI

Isoforms

- Isoform 2 of Eukaryotic initiation factor 4A-II

Sequence View

        10         20         30         40         50         60 
MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA YGFEKPSAIQ 
        70         80         90        100        110        120 
QRAIIPCIKG YDVIAQAQSG TGKTATFAIS ILQQLEIEFK ETQALVLAPT RELAQQIQKV 
       130        140        150        160        170        180 
ILALGDYMGA TCHACIGGTN VRNEMQKLQA EAPHIVVGTP GRVFDMLNRR YLSPKWIKMF 
       190        200        210        220        230        240 
VLDEADEMLS RGFKDQIYEI FQKLNTSIQV VLLSATMPTD VLEVTKKFMR DPIRILVKKE 
       250        260        270        280        290        300 
ELTLEGIKQF YINVEREEWK LDTLCDLYET LTITQAVIFL NTRRKVDWLT EKMHARDFTV 
       310        320        330        340        350        360 
SALHGDMDQK ERDVIMREFR SGSSRVLITT DLLARGIDVQ QVSLVINYDL PTNRENYIHR 
       370        380        390        400    
IGRGGRFGRK GVAINFVTEE DKRILRDIET FYNTTVEEMP MNVADLI



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)