P10923: Osteopontin

General Information

Protein names	- Osteopontin - 2AR - Bone sialoprotein 1 - Calcium oxalate crystal growth inhibitor protein - Early T-lymphocyte activation 1 protein - Minopontin - Secreted phosphoprotein 1 - SPP-1
Gene names	Spp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P10923

3 N-termini

6 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRLAVICFCL FGIASSLPVK VTDSGSSEEK LYSLHPDPIA TWLVPDPSQK QNLLAPQNAV
        70         80         90        100        110        120
SSEEKDDFKQ ETLPSNSNES HDHMDDDDDD DDDDGDHAES EDSVDSDESD ESHHSDESDE
       130        140        150        160        170        180
TVTASTQADT FTPIVPTVDV PNGRGDSLAY GLRSKSRSFQ VSDEQYPDAT DEDLTSHMKS
       190        200        210        220        230        240
GESKESLDVI PVAQLLSMPS DQDNNGKGSH ESSQLDEPSL ETHRLEHSKE SQESADQSDV
       250        260        270        280        290
IDSQASSKAS LEHQSHKFHS HKDKLVLDPK SKEDDRYLKF RISHELESSS SEVN

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P10923-17-unknown	LPVKVT...	17	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P10923-158-unknown	SFQVSD...	158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33322
P10923-195-unknown	LLSMPS...	195	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33323

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPDPSQ	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123163
...SLAYGL	151	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117338
...RSKSRS	157	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33322
...FQVSDE	163	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000108366
...IPVAQL	194	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33323
...SSEVN	294	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	157	KSRS.\|.SFQV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> OSTP_MOUSE @157
MMP2_MOUSE	194	VAQL.\|.LLSM	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)