P11032: Granzyme A

General Information

Protein names	- Granzyme A - 3.4.21.78 - Autocrine thymic lymphoma granzyme-like serine protease - CTLA-3 - Fragmentin-1 - T cell-specific serine protease 1 - TSP-1
Gene names	Gzma
Organism	Mus musculus
Protease Family
Protease ID	S01.135
Chromosome location
UniProt ID	P11032

1 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRNASGPRGP SLATLLFLLL IPEGGCERII GGDTVVPHSR PYMALLKLSS NTICAGALIE
        70         80         90        100        110        120
KNWVLTAAHC NVGKRSKFIL GAHSINKEPE QQILTVKKAF PYPCYDEYTR EGDLQLVRLK
       130        140        150        160        170        180
KKATVNRNVA ILHLPKKGDD VKPGTRCRVA GWGRFGNKSA PSETLREVNI TVIDRKICND
       190        200        210        220        230        240
EKHYNFHPVI GLNMICAGDL RGGKDSCNGD SGSPLLCDGI LRGITSFGGE KCGDRRWPGV
       250        260
YTFLSDKHLN WIKKIMKGSV

Isoforms

- Isoform HF2 of Granzyme A

Sequence View

Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P11032-29-unknown	IIGGDT...	29	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P11032-29-unknown	IIGGDT...	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28623
P11032-29-unknown	IIGGDT...	29	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114555

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGCERI	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28623
...MKGSV	260	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...MKGSV	260	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72001

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATC_MOUSE	28	CERI.\|.IIGG	inferred from experiment	unknown	MEROPS	Ley TJ	Pham CT et al.:Dipeptidyl peptidase I is requi... (C01.070)	10411926,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P11032: Granzyme A

General Information

1

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates