P11152: Lipoprotein lipase

General Information

Protein names	- Lipoprotein lipase - LPL - 3.1.1.34 {ECO:0000269\|PubMed:8675619}
Gene names	Lpl
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P11152

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESKALLLVV LGVWLQSLTA FRGGVAAADA GRDFSDIESK FALRTPEDTA EDTCHLIPGL
        70         80         90        100        110        120
ADSVSNCHFN HSSKTFVVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLYRAQQH
       130        140        150        160        170        180
YPVSAGYTKL VGNDVARFIN WMEEEFNYPL DNVHLLGYSL GAHAAGVAGS LTNKKVNRIT
       190        200        210        220        230        240
GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ
       250        260        270        280        290        300
PGCNIGEAIR VIAERGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CNSKEAFEKG
       310        320        330        340        350        360
LCLSCRKNRC NNLGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTEDGKQHNQ
       370        380        390        400        410        420
AFEISLYGTV AESENIPFTL PEVSTNKTYS FLIYTEVDIG ELLMMKLKWI SDSYFSWPDW
       430        440        450        460        470
WSSPSFVIER IRVKAGETQK KVIFCAREKV SHLQKGKDSA VFVKCHDKSL KKSG

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P11152-28-unknown	ADAGRD...	28	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P11152-159-unmodified	SLGAHA...	159		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P11152-179-unknown	ITGLDP...	179	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33334
P11152-198-unknown	LSPDDA...	198	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33335
P11152-229-unknown	HVDIYP...	229	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33336

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKVNRI	178	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33334
...EAPSRL	197	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33335
...QKPVGH	228	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33336
...LKKSG	474	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	178	VNRI.\|.ITGL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	197	PSRL.\|.LSPD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	228	PVGH.\|.HVDI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)