P11983: T-complex protein 1 subunit alpha

General Information

Protein names	- T-complex protein 1 subunit alpha - TCP-1-alpha - CCT-alpha - Tailless complex polypeptide 1A - TCP-1-A - Tailless complex polypeptide 1B - TCP-1-B
Gene names	Tcp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P11983

6 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGPLSVFGD RSTGEAVRSQ NVMAAASIAN IVKSSFGPVG LDKMLVDDIG DVTITNDGAT
        70         80         90        100        110        120
ILKLLEVEHP AAKVLCELAD LQDKEVGDGT TSVVIIAAEL LKNADELVKQ KIHPTSVISG
       130        140        150        160        170        180
YRLACKEAVR YINENLIINT DELGRDCLIN AAKTSMSSKI IGINGDYFAN MVVDAVLAVK
       190        200        210        220        230        240
YTDARGQPRY PVNSVNILKA HGRSQIESML INGYALNCVV GSQGMPKRIV NAKIACLDFS
       250        260        270        280        290        300
LQKTKMKLGV QVVITDPEKL DQIRQRESDI TKERIQKILA TGANVILTTG GIDDMYLKYF
       310        320        330        340        350        360
VEAGAMAVRR VLKRDLKHVA KASGASILST LANLEGEETF EVTMLGQAEE VVQERICDDE
       370        380        390        400        410        420
LILIKNTKAR TSASIILRGA NDFMCDEMER SLHDALCVVK RVLELKSVVP GGGAVEAALS
       430        440        450        460        470        480
IYLENYATSM GSREQLAIAE FARSLLVIPN TLAVNAAQDS TDLVAKLRAF HNEAQVNPER
       490        500        510        520        530        540
KNLKWIGLDL VHGKPRDNKQ AGVFEPTIVK VKSLKFATEA AITILRIDDL IKLHPESKDD
       550
KHGSYENAVH SGALDD

Isoforms

- Isoform 2 of T-complex protein 1 subunit alpha

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P11983-1-Acetylation	MEGPLS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P11983-217-unknown	NCVVGS...	217		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29698
P11983-217-unknown	NCVVGS...	217		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145435
P11983-219-unknown	VVGSQG...	219		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29700
P11983-219-unknown	VVGSQG...	219		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145516
P11983-453-unknown	AVNAAQ...	453		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29702
P11983-453-unknown	AVNAAQ...	453		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152046
P11983-470-unknown	FHNEAQ...	470		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33353
P11983-470-unknown	FHNEAQ...	470		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152348
P11983-472-unknown	NEAQVN...	472		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33355
P11983-472-unknown	NEAQVN...	472		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152387

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NGYALN	216	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29698
...NGYALN	216	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128728
...YALNCV	218	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29700
...YALNCV	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128813
...IPNTLA	452	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29702
...IPNTLA	452	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135456
...AKLRAF	469	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33353
...AKLRAF	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135759
...LRAFHN	471	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33355
...LRAFHN	471	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135798
...GALDD	556	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GALDD	556	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87367

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	216	YALN.\|.NCVV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPA_MOUSE @216
CATE_MOUSE	218	LNCV.\|.VVGS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPA_MOUSE @218
CATE_MOUSE	452	NTLA.\|.AVNA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPA_MOUSE @452
MMP2_MOUSE	469	LRAF.\|.FHNE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	471	AFHN.\|.NEAQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)