P12388: Plasminogen activator inhibitor 2, macrophage
| Protein names | - Plasminogen activator inhibitor 2, macrophage - PAI-2 - Serpin B2 |
|---|---|
| Gene names | Serpinb2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | I04.007 |
| Chromosome location | |
| UniProt ID | P12388 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEELSMANTM FALNLLKQIE KSNSTQNIFI SPWSISSTLA IVLLGAGGNT EQQMAKVLQF
70 80 90 100 110 120
NEIGSYGITT RNPENFSGCD FAQQIQKENY PSAILQAQAG DKIHSAFSSL SSTINTPQGD
130 140 150 160 170 180
YLLESANKLF GEKSARFKEE YIQLSKKYYS TEPEAVDFLE CAEEAREKIN SWVKTQTKGE
190 200 210 220 230 240
IPNLLPEGSV DEDTKMVLVN AVYFKGKWKT PFEKKLNGLY PFRVNSHESI PVQMMFLHAK
250 260 270 280 290 300
LNIGYIKDLK TQILELPHTG NISMLLLLPD EIEDASTGLE LLESEINFAN FNKWISKDTL
310 320 330 340 350 360
DEDDVVVYIP KFKLAQSYEL KSILQSMGME DAFNKGKANF SGMSERNDLF LSEVFHQASV
370 380 390 400 410
DVTEEGTVAA GGTGAVMTGR TGHGGPQFVA DHPFLFFIMD KITHTILFVG RFSSP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P12388-1-unknown | MEELSM... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P12388-123-unknown | LESANK... | 123 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29706 | |||
| P12388-334-unknown | NKGKAN... | 334 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28753 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QGDYLL | 122 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29706 | |||
| ...MEDAFN | 333 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28753 | |||
| ...RFSSP | 415 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 122 | DYLL.|.LESA | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PAI2_MOUSE @122 | ||
| CATD_MOUSE | 333 | DAFN.|.NKGK | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> PAI2_MOUSE @333 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|