P13473: Lysosome-associated membrane glycoprotein 2
Protein names | - Lysosome-associated membrane glycoprotein 2 - LAMP-2 - Lysosome-associated membrane protein 2 - CD107 antigen-like family member B - LGP-96 {ECO:0000303|PubMed:8662539} - CD107b |
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Gene names | LAMP2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P13473 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVCFRLFPVP GSGLVLVCLV LGAVRSYALE LNLTDSENAT CLYAKWQMNF TVRYETTNKT
70 80 90 100 110 120
YKTVTISDHG TVTYNGSICG DDQNGPKIAV QFGPGFSWIA NFTKAASTYS IDSVSFSYNT
130 140 150 160 170 180
GDNTTFPDAE DKGILTVDEL LAIRIPLNDL FRCNSLSTLE KNDVVQHYWD VLVQAFVQNG
190 200 210 220 230 240
TVSTNEFLCD KDKTSTVAPT IHTTVPSPTT TPTPKEKPEA GTYSVNNGND TCLLATMGLQ
250 260 270 280 290 300
LNITQDKVAS VININPNTTH STGSCRSHTA LLRLNSSTIK YLDFVFAVKN ENRFYLKEVN
310 320 330 340 350 360
ISMYLVNGSV FSIANNNLSY WDAPLGSSYM CNKEQTVSVS GAFQINTFDL RVQPFNVTQG
370 380 390 400 410
KYSTAQDCSA DDDNFLVPIA VGAALAGVLI LVLLAYFIGL KHHHAGYEQF
Isoforms
- Isoform LAMP-2B of Lysosome-associated membrane glycoprotein 2 - Isoform LAMP-2C of Lysosome-associated membrane glycoprotein 2Sequence View
10 20 30 40 50 60
MVCFRLFPVP GSGLVLVCLV LGAVRSYALE LNLTDSENAT CLYAKWQMNF TVRYETTNKT
70 80 90 100 110 120
YKTVTISDHG TVTYNGSICG DDQNGPKIAV QFGPGFSWIA NFTKAASTYS IDSVSFSYNT
130 140 150 160 170 180
GDNTTFPDAE DKGILTVDEL LAIRIPLNDL FRCNSLSTLE KNDVVQHYWD VLVQAFVQNG
190 200 210 220 230 240
TVSTNEFLCD KDKTSTVAPT IHTTVPSPTT TPTPKEKPEA GTYSVNNGND TCLLATMGLQ
250 260 270 280 290 300
LNITQDKVAS VININPNTTH STGSCRSHTA LLRLNSSTIK YLDFVFAVKN ENRFYLKEVN
310 320 330 340 350 360
ISMYLVNGSV FSIANNNLSY WDAPLGSSYM CNKEQTVSVS GAFQINTFDL RVQPFNVTQG
370 380 390 400 410
KYSTAQDCSA DDDNFLVPIA VGAALAGVLI LVLLAYFIGL KHHHAGYEQF
10 20 30 40 50 60
MVCFRLFPVP GSGLVLVCLV LGAVRSYALE LNLTDSENAT CLYAKWQMNF TVRYETTNKT
70 80 90 100 110 120
YKTVTISDHG TVTYNGSICG DDQNGPKIAV QFGPGFSWIA NFTKAASTYS IDSVSFSYNT
130 140 150 160 170 180
GDNTTFPDAE DKGILTVDEL LAIRIPLNDL FRCNSLSTLE KNDVVQHYWD VLVQAFVQNG
190 200 210 220 230 240
TVSTNEFLCD KDKTSTVAPT IHTTVPSPTT TPTPKEKPEA GTYSVNNGND TCLLATMGLQ
250 260 270 280 290 300
LNITQDKVAS VININPNTTH STGSCRSHTA LLRLNSSTIK YLDFVFAVKN ENRFYLKEVN
310 320 330 340 350 360
ISMYLVNGSV FSIANNNLSY WDAPLGSSYM CNKEQTVSVS GAFQINTFDL RVQPFNVTQG
370 380 390 400 410
KYSTAQDCSA DDDNFLVPIA VGAALAGVLI LVLLAYFIGL KHHHAGYEQF
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P13473-1-unknown | MVCFRL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79342 | |||
P13473-1-unknown | MVCFRL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79343 | |||
P13473-29-unknown | LELNLT... | 29 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P13473-29-unknown | LELNLT... | 29 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114491 | |||
P13473-29-unknown | LELNLT... | 29 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114492 | |||
P13473-376-unknown | LVPIAV... | 376 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27629 | |||
P13473-376-unknown | LVPIAV... | 376 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...DDDNFL | 375 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27629 | |||
...GYEQF | 410 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
PPGB_HUMAN | 375 | DNFL.|.LVPI | inferred from experiment | unknown | MEROPS | Dice JF | Cuervo AM et al.:Cathepsin A regulates chaperone... (S10.002) | 12505983, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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