P13647: Keratin, type II cytoskeletal 5

General Information

Protein names	- Keratin, type II cytoskeletal 5 - 58 kDa cytokeratin - Cytokeratin-5 - CK-5 - Keratin-5 - K5 - Type-II keratin Kb5
Gene names	KRT5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P13647

2 N-termini

6 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRQSSVSFR SGGSRSFSTA SAITPSVSRT SFTSVSRSGG GGGGGFGRVS LAGACGVGGY
        70         80         90        100        110        120
GSRSLYNLGG SKRISISTSG GSFRNRFGAG AGGGYGFGGG AGSGFGFGGG AGGGFGLGGG
       130        140        150        160        170        180
AGFGGGFGGP GFPVCPPGGI QEVTVNQSLL TPLNLQIDPS IQRVRTEERE QIKTLNNKFA
       190        200        210        220        230        240
SFIDKVRFLE QQNKVLDTKW TLLQEQGTKT VRQNLEPLFE QYINNLRRQL DSIVGERGRL
       250        260        270        280        290        300
DSELRNMQDL VEDFKNKYED EINKRTTAEN EFVMLKKDVD AAYMNKVELE AKVDALMDEI
       310        320        330        340        350        360
NFMKMFFDAE LSQMQTHVSD TSVVLSMDNN RNLDLDSIIA EVKAQYEEIA NRSRTEAESW
       370        380        390        400        410        420
YQTKYEELQQ TAGRHGDDLR NTKHEISEMN RMIQRLRAEI DNVKKQCANL QNAIADAEQR
       430        440        450        460        470        480
GELALKDARN KLAELEEALQ KAKQDMARLL REYQELMNTK LALDVEIATY RKLLEGEECR
       490        500        510        520        530        540
LSGEGVGPVN ISVVTSSVSS GYGSGSGYGG GLGGGLGGGL GGGLAGGSSG SYYSSSSGGV
       550        560        570        580        590
GLGGGLSVGG SGFSASSGRG LGVGFGSGGG SSSSVKFVST TSSSRKSFKS

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 6 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P13647-1-unknown	MSRQSS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P13647-336-unknown	DSIIAE...	336		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18723

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGPGFP	132	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000449651
...KFASFI	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000448041
...MNKVEL	288	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447209
...RNLDLD	335	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18723
...DDLRNT	381	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000449783
...KSFKS	590	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	335	LDLD.\|.DSII	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)