P14151: L-selectin
Protein names | - L-selectin - CD62 antigen-like family member L - Leukocyte adhesion molecule 1 - LAM-1 {ECO:0000303|PubMed:2473156} - Leukocyte surface antigen Leu-8 - Leukocyte-endothelial cell adhesion molecule 1 - LECAM1 - Lymph node homing receptor {ECO:0000303|PubMed:2663882} - TQ1 {ECO:0000303|PubMed:1692315, ECO:0000303|PubMed:2509939} - gp90-MEL - CD62L |
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Gene names | SELL |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P14151 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MIFPWKCQST QRDLWNIFKL WGWTMLCCDF LAHHGTDCWT YHYSEKPMNW QRARRFCRDN
70 80 90 100 110 120
YTDLVAIQNK AEIEYLEKTL PFSRSYYWIG IRKIGGIWTW VGTNKSLTEE AENWGDGEPN
130 140 150 160 170 180
NKKNKEDCVE IYIKRNKDAG KWNDDACHKL KAALCYTASC QPWSCSGHGE CVEIINNYTC
190 200 210 220 230 240
NCDVGYYGPQ CQFVIQCEPL EAPELGTMDC THPLGNFSFS SQCAFSCSEG TNLTGIEETT
250 260 270 280 290 300
CGPFGNWSSP EPTCQVIQCE PLSAPDLGIM NCSHPLASFS FTSACTFICS EGTELIGKKK
310 320 330 340 350 360
TICESSGIWS NPSPICQKLD KSFSMIKEGD YNPLFIPVAV MVTAFSGLAF IIWLARRLKK
370
GKKSKRSMND PY
Isoforms
- Isoform 2 of L-selectinSequence View
10 20 30 40 50 60
MIFPWKCQST QRDLWNIFKL WGWTMLCCDF LAHHGTDCWT YHYSEKPMNW QRARRFCRDN
70 80 90 100 110 120
YTDLVAIQNK AEIEYLEKTL PFSRSYYWIG IRKIGGIWTW VGTNKSLTEE AENWGDGEPN
130 140 150 160 170 180
NKKNKEDCVE IYIKRNKDAG KWNDDACHKL KAALCYTASC QPWSCSGHGE CVEIINNYTC
190 200 210 220 230 240
NCDVGYYGPQ CQFVIQCEPL EAPELGTMDC THPLGNFSFS SQCAFSCSEG TNLTGIEETT
250 260 270 280 290 300
CGPFGNWSSP EPTCQVIQCE PLSAPDLGIM NCSHPLASFS FTSACTFICS EGTELIGKKK
310 320 330 340 350 360
TICESSGIWS NPSPICQKLD KSFSMIKEGD YNPLFIPVAV MVTAFSGLAF IIWLARRLKK
370
GKKSKRSMND PY
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P14151-39-unknown | WTYHYS... | 39 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P14151-39-unknown | WTYHYS... | 39 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt115379 | |||
P14151-322-unknown | SFSMIK... | 322 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC134 | |||
P14151-322-unknown | SFSMIK... | 322 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150618 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QKLDKS | 321 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC134 | |||
...QKLDKS | 321 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134016 | |||
...MNDPY | 372 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...MNDPY | 372 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt75718 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
ADA17_HUMAN | 321 | LDKS.|.SFSM | inferred from experiment | unknown | MEROPS | Black RA | Peschon JJ et al.:An essential role for ectodomai... (M12.217) | 9812885, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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