P16144: Integrin beta-4
Protein names | - Integrin beta-4 - GP150 - CD104 |
---|---|
Gene names | ITGB4 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P16144 |
4
N-termini
3
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR
70 80 90 100 110 120
CNTQAELLAA GCQRESIVVM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL
130 140 150 160 170 180
EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV
190 200 210 220 230 240
PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL
250 260 270 280 290 300
QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR
310 320 330 340 350 360
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE
370 380 390 400 410 420
EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG
430 440 450 460 470 480
THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV
490 500 510 520 530 540
CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN
550 560 570 580 590 600
FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR
610 620 630 640 650 660
CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE
670 680 690 700 710 720
LKRAEEVVVR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL
730 740 750 760 770 780
LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR
790 800 810 820 830 840
SGNLKGRDVV RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC
850 860 870 880 890 900
AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK
910 920 930 940 950 960
LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL
970 980 990 1000 1010 1020
LVEAIDVPAG TATLGRRLVN ITIIKEQARD VVSFEQPEFS VSRGDQVARI PVIRRVLDGG
1030 1040 1050 1060 1070 1080
KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH
1090 1100 1110 1120 1130 1140
VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS
1150 1160 1170 1180 1190 1200
RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG
1210 1220 1230 1240 1250 1260
AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV
1270 1280 1290 1300 1310 1320
NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP
1330 1340 1350 1360 1370 1380
KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG
1390 1400 1410 1420 1430 1440
EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPHGPPDDG GAGGKGGSLP RSATPGPPGE
1450 1460 1470 1480 1490 1500
HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH
1510 1520 1530 1540 1550 1560
SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY
1570 1580 1590 1600 1610 1620
SVEYQLLNGG ELHRLNIPNP AQTSVVVEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES
1630 1640 1650 1660 1670 1680
QVHPQSPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM
1690 1700 1710 1720 1730 1740
AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG
1750 1760 1770 1780 1790 1800
PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF
1810 1820
VSRTLTTSGT LSTHMDQQFF QT
Isoforms
- Isoform Beta-4A of Integrin beta-4 - Isoform Beta-4B of Integrin beta-4 - Isoform Beta-4D of Integrin beta-4 - Isoform Beta-4E of Integrin beta-4Sequence View
10 20 30 40 50 60
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR
70 80 90 100 110 120
CNTQAELLAA GCQRESIVVM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL
130 140 150 160 170 180
EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV
190 200 210 220 230 240
PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL
250 260 270 280 290 300
QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR
310 320 330 340 350 360
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE
370 380 390 400 410 420
EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG
430 440 450 460 470 480
THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV
490 500 510 520 530 540
CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN
550 560 570 580 590 600
FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR
610 620 630 640 650 660
CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE
670 680 690 700 710 720
LKRAEEVVVR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL
730 740 750 760 770 780
LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR
790 800 810 820 830 840
SGNLKGRDVV RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC
850 860 870 880 890 900
AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK
910 920 930 940 950 960
LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL
970 980 990 1000 1010 1020
LVEAIDVPAG TATLGRRLVN ITIIKEQARD VVSFEQPEFS VSRGDQVARI PVIRRVLDGG
1030 1040 1050 1060 1070 1080
KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH
1090 1100 1110 1120 1130 1140
VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS
1150 1160 1170 1180 1190 1200
RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG
1210 1220 1230 1240 1250 1260
AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV
1270 1280 1290 1300 1310 1320
NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP
1330 1340 1350 1360 1370 1380
KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG
1390 1400 1410 1420 1430 1440
EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPHGPPDDG GAGGKGGSLP RSATPGPPGE
1450 1460 1470 1480 1490 1500
HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH
1510 1520 1530 1540 1550 1560
SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY
1570 1580 1590 1600 1610 1620
SVEYQLLNGG ELHRLNIPNP AQTSVVVEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES
1630 1640 1650 1660 1670 1680
QVHPQSPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM
1690 1700 1710 1720 1730 1740
AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG
1750 1760 1770 1780 1790 1800
PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF
1810 1820
VSRTLTTSGT LSTHMDQQFF QT
10 20 30 40 50 60
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR
70 80 90 100 110 120
CNTQAELLAA GCQRESIVVM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL
130 140 150 160 170 180
EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV
190 200 210 220 230 240
PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL
250 260 270 280 290 300
QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR
310 320 330 340 350 360
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE
370 380 390 400 410 420
EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG
430 440 450 460 470 480
THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV
490 500 510 520 530 540
CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN
550 560 570 580 590 600
FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR
610 620 630 640 650 660
CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE
670 680 690 700 710 720
LKRAEEVVVR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL
730 740 750 760 770 780
LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR
790 800 810 820 830 840
SGNLKGRDVV RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC
850 860 870 880 890 900
AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK
910 920 930 940 950 960
LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL
970 980 990 1000 1010 1020
LVEAIDVPAG TATLGRRLVN ITIIKEQARD VVSFEQPEFS VSRGDQVARI PVIRRVLDGG
1030 1040 1050 1060 1070 1080
KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH
1090 1100 1110 1120 1130 1140
VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS
1150 1160 1170 1180 1190 1200
RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG
1210 1220 1230 1240 1250 1260
AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV
1270 1280 1290 1300 1310 1320
NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP
1330 1340 1350 1360 1370 1380
KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG
1390 1400 1410 1420 1430 1440
EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPHGPPDDG GAGGKGGSLP RSATPGPPGE
1450 1460 1470 1480 1490 1500
HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH
1510 1520 1530 1540 1550 1560
SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY
1570 1580 1590 1600 1610 1620
SVEYQLLNGG ELHRLNIPNP AQTSVVVEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES
1630 1640 1650 1660 1670 1680
QVHPQSPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM
1690 1700 1710 1720 1730 1740
AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG
1750 1760 1770 1780 1790 1800
PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF
1810 1820
VSRTLTTSGT LSTHMDQQFF QT
10 20 30 40 50 60
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR
70 80 90 100 110 120
CNTQAELLAA GCQRESIVVM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL
130 140 150 160 170 180
EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV
190 200 210 220 230 240
PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL
250 260 270 280 290 300
QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR
310 320 330 340 350 360
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE
370 380 390 400 410 420
EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG
430 440 450 460 470 480
THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV
490 500 510 520 530 540
CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN
550 560 570 580 590 600
FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR
610 620 630 640 650 660
CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE
670 680 690 700 710 720
LKRAEEVVVR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL
730 740 750 760 770 780
LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR
790 800 810 820 830 840
SGNLKGRDVV RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC
850 860 870 880 890 900
AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK
910 920 930 940 950 960
LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL
970 980 990 1000 1010 1020
LVEAIDVPAG TATLGRRLVN ITIIKEQARD VVSFEQPEFS VSRGDQVARI PVIRRVLDGG
1030 1040 1050 1060 1070 1080
KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH
1090 1100 1110 1120 1130 1140
VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS
1150 1160 1170 1180 1190 1200
RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG
1210 1220 1230 1240 1250 1260
AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV
1270 1280 1290 1300 1310 1320
NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP
1330 1340 1350 1360 1370 1380
KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG
1390 1400 1410 1420 1430 1440
EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPHGPPDDG GAGGKGGSLP RSATPGPPGE
1450 1460 1470 1480 1490 1500
HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH
1510 1520 1530 1540 1550 1560
SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY
1570 1580 1590 1600 1610 1620
SVEYQLLNGG ELHRLNIPNP AQTSVVVEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES
1630 1640 1650 1660 1670 1680
QVHPQSPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM
1690 1700 1710 1720 1730 1740
AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG
1750 1760 1770 1780 1790 1800
PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF
1810 1820
VSRTLTTSGT LSTHMDQQFF QT
10 20 30 40 50 60
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR
70 80 90 100 110 120
CNTQAELLAA GCQRESIVVM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL
130 140 150 160 170 180
EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV
190 200 210 220 230 240
PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL
250 260 270 280 290 300
QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR
310 320 330 340 350 360
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE
370 380 390 400 410 420
EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG
430 440 450 460 470 480
THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV
490 500 510 520 530 540
CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN
550 560 570 580 590 600
FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR
610 620 630 640 650 660
CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE
670 680 690 700 710 720
LKRAEEVVVR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL
730 740 750 760 770 780
LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR
790 800 810 820 830 840
SGNLKGRDVV RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC
850 860 870 880 890 900
AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK
910 920 930 940 950 960
LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL
970 980 990 1000 1010 1020
LVEAIDVPAG TATLGRRLVN ITIIKEQARD VVSFEQPEFS VSRGDQVARI PVIRRVLDGG
1030 1040 1050 1060 1070 1080
KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH
1090 1100 1110 1120 1130 1140
VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS
1150 1160 1170 1180 1190 1200
RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG
1210 1220 1230 1240 1250 1260
AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV
1270 1280 1290 1300 1310 1320
NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP
1330 1340 1350 1360 1370 1380
KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG
1390 1400 1410 1420 1430 1440
EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPHGPPDDG GAGGKGGSLP RSATPGPPGE
1450 1460 1470 1480 1490 1500
HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH
1510 1520 1530 1540 1550 1560
SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY
1570 1580 1590 1600 1610 1620
SVEYQLLNGG ELHRLNIPNP AQTSVVVEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES
1630 1640 1650 1660 1670 1680
QVHPQSPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM
1690 1700 1710 1720 1730 1740
AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG
1750 1760 1770 1780 1790 1800
PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF
1810 1820
VSRTLTTSGT LSTHMDQQFF QT
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P16144-1-unknown | MAGPRP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78163 | |||
P16144-1-unknown | MAGPRP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78164 | |||
P16144-1-unknown | MAGPRP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78165 | |||
P16144-1-unknown | MAGPRP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78166 | |||
P16144-28-unknown | NRCKKA... | 28 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P16144-28-unknown | NRCKKA... | 28 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114414 | |||
P16144-28-unknown | NRCKKA... | 28 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114415 | |||
P16144-28-unknown | NRCKKA... | 28 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114416 | |||
P16144-28-unknown | NRCKKA... | 28 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114417 | |||
P16144-445-unknown | KMDAGI... | 445 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC24714 | |||
P16144-445-unknown | KMDAGI... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152716 | |||
P16144-445-unknown | KMDAGI... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152717 | |||
P16144-445-unknown | KMDAGI... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152718 | |||
P16144-445-unknown | KMDAGI... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152719 | |||
P16144-1110-unknown | RSFTSQ... | 1110 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2817 | |||
P16144-1110-unknown | RSFTSQ... | 1110 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1666 | |||
P16144-1110-unknown | RSFTSQ... | 1110 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157414 | |||
P16144-1110-unknown | RSFTSQ... | 1110 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157415 | |||
P16144-1110-unknown | RSFTSQ... | 1110 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157416 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...FSDGLK | 444 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC24714 | |||
...FSDGLK | 444 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136136 | |||
...FSDGLK | 444 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136137 | |||
...FSDGLK | 444 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136138 | |||
...FSDGLK | 444 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136139 | |||
...PDELDR | 1109 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2817 | |||
...PDELDR | 1109 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1666 | |||
...PDELDR | 1109 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140912 | |||
...PDELDR | 1109 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140913 | |||
...PDELDR | 1109 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140914 | |||
...QFFQT | 1822 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QFFQT | 1822 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73783 | |||
...QFFQT | 1822 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73781 | |||
...QFFQT | 1822 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73782 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MMP7_HUMAN | 444 | DGLK.|.KMDA | inferred from experiment | unknown | MEROPS | Cress AE | von Bredow DC et al.:Cleavage of beta 4 integrin by ... (M10.008) | 9344615, |
CASP7_HUMAN | 1109 | ELDR.|.RSFT | inferred from experiment | unknown | MEROPS | Cryns VL | Werner ME et al.:Caspase proteolysis of the inte... (C14.003) | 17178732, |
CASP3_HUMAN | 1109 | ELDR.|.RSFT | inferred from experiment | unknown | MEROPS | Cryns VL | Werner ME et al.:Caspase proteolysis of the inte... (C14.003) | 17178732, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|