P17861: X-box-binding protein 1 {ECO:0000303|PubMed:2321018, ECO:0000312|HGNC:HGNC:12801}

General Information

Protein names	- X-box-binding protein 1 {ECO:0000303\|PubMed:2321018, ECO:0000312\|HGNC:HGNC:12801} - XBP-1 {ECO:0000303\|PubMed:2321018} - Tax-responsive element-binding protein 5 {ECO:0000303\|PubMed:2196176} - TREB-5 {ECO:0000303\|PubMed:2196176} - X-box-binding protein 1, cytoplasmic form {ECO:0000303\|PubMed:25239945} - X-box-binding protein 1, luminal form {ECO:0000303\|PubMed:25239945}
Gene names	XBP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P17861

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVVVAAAPNP ADGTPKVLLL SGQPASAAGA PAGQALPLMV PAQRGASPEA ASGGLPQARK
        70         80         90        100        110        120
RQRLTHLSPE EKALRRKLKN RVAAQTARDR KKARMSELEQ QVVDLEEENQ KLLLENQLLR
       130        140        150        160        170        180
EKTHGLVVEN QELRQRLGMD ALVAEEEAEA KGNEVRPVAG SAESAALRLR APLQQVQAQL
       190        200        210        220        230        240
SPLQNISPWI LAVLTLQIQS LISCWAFWTT WTQSCSSNAL PQSLPAWRSS QRSTQKDPVP
       250        260
YQPPFLCQWG RHQPSWKPLM N

Isoforms

- Isoform 2 of X-box-binding protein 1

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P17861-1-unknown	MVVVAA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17861-1-unknown	MVVVAA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94703
P17861-2-	VVVAAA...	2		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P17861-2-	VVVAAA...	2		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P17861-2-	VVVAAA...	2		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P17861-2-unknown	VVVAAA...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175707

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KPLMN	261	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)