P17947: Transcription factor PU.1

General Information

Protein names	- Transcription factor PU.1 - 31 kDa-transforming protein
Gene names	SPI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P17947

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLQACKMEGF PLVPPPSEDL VPYDTDLYQR QTHEYYPYLS SDGESHSDHY WDFHPHHVHS
        70         80         90        100        110        120
EFESFAENNF TELQSVQPPQ LQQLYRHMEL EQMHVLDTPM VPPHPSLGHQ VSYLPRMCLQ
       130        140        150        160        170        180
YPSLSPAQPS SDEEEGERQS PPLEVSDGEA DGLEPGPGLL PGETGSKKKI RLYQFLLDLL
       190        200        210        220        230        240
RSGDMKDSIW WVDKDKGTFQ FSSKHKEALA HRWGIQKGNR KKMTYQKMAR ALRNYGKTGE
       250        260        270
VKKVKKKLTY QFSGEVLGRG GLAERRHPPH

Isoforms

- Isoform 2 of Transcription factor PU.1

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P17947-1-unknown	MLQACK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17947-75-	SVQPPQ...	75		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P17947-75-unknown	SVQPPQ...	75	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178049
P17947-100-unknown	MVPPHP...	100	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165750
P17947-100-	MVPPHP...	100		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P17947-100-	MVPPHP...	100		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P17947-100-	MVPPHP...	100		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P17947-100-	MVPPHP...	100		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P17947-100-	MVPPHP...	100		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RHPPH	270	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...RHPPH	270	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86070

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)