P18887: DNA repair protein XRCC1

General Information

Protein names	- DNA repair protein XRCC1 - X-ray repair cross-complementing protein 1
Gene names	XRCC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P18887

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQLE KEEQIHSVDI
        70         80         90        100        110        120
GNDGSAFVEV LVGSSAGGAG EQDYEVLLVT SSFMSPSESR SGSNPNRVRM FGPDKLVRAA
       130        140        150        160        170        180
AEKRWDRVKI VCSQPYSKDS PFGLSFVRFH SPPDKDEAEA PSQKVTVTKL GQFRVKEEDE
       190        200        210        220        230        240
SANSLRPGAL FFSRINKTSP VTASDPAGPS YAAATLQASS AASSASPVSR AIGSTSKPQE
       250        260        270        280        290        300
SPKGKRKLDL NQEEKKTPSK PPAQLSPSVP KRPKLPAPTR TPATAPVPAR AQGAVTGKPR
       310        320        330        340        350        360
GEGTEPRRPR AGPEELGKIL QGVVVVLSGF QNPFRSELRD KALELGAKYR PDWTRDSTHL
       370        380        390        400        410        420
ICAFANTPKY SQVLGLGGRI VRKEWVLDCH RMRRRLPSRR YLMAGPGSSS EEDEASHSGG
       430        440        450        460        470        480
SGDEAPKLPQ KQPQTKTKPT QAAGPSSPQK PPTPEETKAA SPVLQEDIDI EGVQSEGQDN
       490        500        510        520        530        540
GAEDSGDTED ELRRVAEQKE HRLPPGQEEN GEDPYAGSTD ENTDSEEHQE PPDLPVPELP
       550        560        570        580        590        600
DFFQGKHFFL YGEFPGDERR KLIRYVTAFN GELEDNMSDR VQFVITAQEW DPSFEEALMD
       610        620        630
NPSLAFVRPR WIYSCNEKQK LLPHQLYGVV PQA

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P18887-1-unknown	MPEIRL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P18887-231-	AIGSTS...	231		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P18887-231-	AIGSTS...	231		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DPAGPS	209	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471159
...RAIGST	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472128
...TPATAP	285	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470045
...VVPQA	633	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)