P19137: Laminin subunit alpha-1
Protein names | - Laminin subunit alpha-1 - Laminin A chain - Laminin-1 subunit alpha - Laminin-3 subunit alpha - S-laminin subunit alpha - S-LAM alpha |
---|---|
Gene names | Lama1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P19137 |
5
N-termini
5
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRGSGTGAAL LVLLASVLWV TVRSQQRGLF PAILNLATNA HISANATCGE KGPEMFCKLV
70 80 90 100 110 120
EHVPGRPVRH AQCRVCDGNS TNPRERHPIS HAIDGTNNWW QSPSIQNGRE YHWVTVTLDL
130 140 150 160 170 180
RQVFQVAYII IKAANAPRPG NWILERSVDG VKFKPWQYYA VSDTECLTRY KITPRRGPPT
190 200 210 220 230 240
YRADNEVICT SYYSKLVPLE HGEIHTSLIN GRPSADDPSP QLLEFTSARY IRLRLQRIRT
250 260 270 280 290 300
LNADLMTLSH RDLRDLDPIV TRRYYYSIKD ISVGGMCICY GHASSCPWDE EAKQLQCQCE
310 320 330 340 350 360
HNTCGESCDR CCPGYHQQPW RPGTISSGNE CEECNCHNKA KDCYYDSSVA KERRSLNTAG
370 380 390 400 410 420
QYSGGGVCVN CSQNTTGINC ETCIDQYYRP HKVSPYDDHP CRPCNCDPVG SLSSVCIKDD
430 440 450 460 470 480
RHADLANGKW PGQCPCRKGY AGDKCDRCQF GYRGFPNCIP CDCRTVGSLN EDPCIEPCLC
490 500 510 520 530 540
KKNVEGKNCD RCKPGFYNLK ERNPEGCSEC FCFGVSGVCD SLTWSISQVT NMSGWLVTDL
550 560 570 580 590 600
MSTNKIRSQQ DVLGGHRQIS INNTAVMQRL TSTYYWAAPE AYLGNKLTAF GGFLKYTVSY
610 620 630 640 650 660
DIPVETVDSD LMSHADIIIK GNGLTISTRA EGLSLQPYEE YFNVVRLVPE NFRDFDTRRE
670 680 690 700 710 720
IDRDQLMTVL ANVTHLLIRA NYNSAKMALY RLDSVSLDIA SPNAIDLAVA ADVEHCECPQ
730 740 750 760 770 780
GYTGTSCEAC LPGYYRVDGI LFGGICQPCE CHGHASECDI HGICSVCTHN TTGDHCEQCL
790 800 810 820 830 840
PGFYGTPSRG TPGDCQPCAC PLSIDSNNFS PTCHLTDGEE VVCDQCAPGY SGSWCERCAD
850 860 870 880 890 900
GYYGNPTVPG GTCVPCNCSG NVDPLEAGHC DSVTGECLKC LWNTDGAHCE RCADGFYGDA
910 920 930 940 950 960
VTAKNCRACD CHENGSLSGI CHLETGLCDC KPHVTGQQCD QCLSGYYGLD TGLGCVPCNC
970 980 990 1000 1010 1020
SVEGSVSDNC TEEGQCHCGP GVSGKQCDRC SHGFYAFQDG GCTPCDCAHT QNNCDPASGE
1030 1040 1050 1060 1070 1080
CLCPPHTQGL KCEECEEAYW GLDPEQGCQA CNCSAVGSTS AQCDVLSGHC PCKKGFGGQS
1090 1100 1110 1120 1130 1140
CHQCSLGYRS FPDCVPCGCD LRGTLPDTCD LEQGLCSCSE DGGTCSCKEN AVGPQCSKCQ
1150 1160 1170 1180 1190 1200
AGTFALRGDN PQGCSPCFCF GLSQLCSELE GYVRTLITLA SDQPLLHVVS QSNLKGTIEG
1210 1220 1230 1240 1250 1260
VHFQPPDTLL DAEAVRQHIY AEPFYWRLPK QFQGDQLLAY GGKLQYSVAF YSTLGTGTSN
1270 1280 1290 1300 1310 1320
YEPQVLIKGG RARKHVIYMD APAPENGVRQ DYEVRMKEEF WKYFNSVSEK HVTHSDFMSV
1330 1340 1350 1360 1370 1380
LSNIDYILIK ASYGQGLQQS RIANISMEVG RKAVELPAEG EAALLLELCV CPPGTAGHSC
1390 1400 1410 1420 1430 1440
QDCAPGYYRE KLPESGGRGP RPLLAPCVPC NCNNHSDVCD PETGKCLSCR DHTSGDHCEL
1450 1460 1470 1480 1490 1500
CASGYYGKVT GLPGDCTPCT CPHHPPFSFS PTCVVEGDSD FRCNACLPGY EGQYCERCSA
1510 1520 1530 1540 1550 1560
GYHGNPRAAG GSCQTCDCNP QGSVHSDCDR ASGQCVCKPG ATGLHCEKCL PRHILMESDC
1570 1580 1590 1600 1610 1620
VSCDDDCVGP LLNDLDSVGD AVLSLNLTGV SPAPYGILEN LENTTKYFQR YLIKENAKKI
1630 1640 1650 1660 1670 1680
RAEIQLEGIA EQTENLQKEL TRVLARHQKV NAEMERTSNG TQALATFIEQ LHANIKEITE
1690 1700 1710 1720 1730 1740
KVATLNQTAR KDFQPPVSAL QSMHQNISSL LGLIKERNFT EMQQNATLEL KAAKDLLSRI
1750 1760 1770 1780 1790 1800
QKRFQKPQEK LKALKEANSL LSNHSEKLQA AEELLKEAGS KTQESNLLLL LVKANLKEFQ
1810 1820 1830 1840 1850 1860
EKKLRVQEEQ NVTSELIAKG REWVDAAGTH TAAAQDTLTQ LEHHRDELLL WARKIRSHVD
1870 1880 1890 1900 1910 1920
DLVMQMSKRR ARDLVHRAEQ HASELQSRAG ALDRDLENVR NVSLNATSAA HVHSNIQTLT
1930 1940 1950 1960 1970 1980
EEAEMLAADA HKTANKTDLI SESLASRGKA VLQRSSRFLK ESVSTRRKQQ GITMKLDELK
1990 2000 2010 2020 2030 2040
NLTSQFQESM DNIMKQANDS LAMLRESPGG MREKGRKARE LAAAANESAV KTLEDVLALS
2050 2060 2070 2080 2090 2100
LRVFNTSEDL SRVNATVQET NDLLHNSTMT TLLAGRKMKD MEMQANLLLD RLKPLKTLEE
2110 2120 2130 2140 2150 2160
NLSRNLSEIK LLISRARKQV ASIKVAVSAD RDCIRAYQPQ TSSTNYNTLI LNVKTQEPDN
2170 2180 2190 2200 2210 2220
LLFYLGSSSS SDFLAVEMRR GKVAFLWDLG SGSTRLEFPE VSINNNRWHS IYITRFGNMG
2230 2240 2250 2260 2270 2280
SLSVKEASAA ENPPVRTSKS PGPSKVLDIN NSTLMFVGGL GGQIKKSPAV KVTHFKGCMG
2290 2300 2310 2320 2330 2340
EAFLNGKSIG LWNYIEREGK CNGCFGSSQN EDSSFHFDGS GYAMVEKTLR PTVTQIVILF
2350 2360 2370 2380 2390 2400
STFSPNGLLF YLASNGTKDF LSIELVRGRV KVMVDLGSGP LTLMTDRRYN NGTWYKIAFQ
2410 2420 2430 2440 2450 2460
RNRKQGLLAV FDAYDTSDKE TKQGETPGAA SDLNRLEKDL IYVGGLPHSK AVRKGVSSRS
2470 2480 2490 2500 2510 2520
YVGCIKNLEI SRSTFDLLRN SYGVRKGCAL EPIQSVSFLR GGYVEMPPKS LSPESSLLAT
2530 2540 2550 2560 2570 2580
FATKNSSGIL LVALGKDAEE AGGAQAHVPF FSIMLLEGRI EVHVNSGDGT SLRKALLHAP
2590 2600 2610 2620 2630 2640
TGSYSDGQEH SISLVRNRRV ITIQVDENSP VEMKLGPLTE GKTIDISNLY IGGLPEDKAT
2650 2660 2670 2680 2690 2700
PMLKMRTSFH GCIKNVVLDA QLLDFTHATG SEQVELDTCL LAEEPMQSLH REHGELPPEP
2710 2720 2730 2740 2750 2760
PTLPQPELCA VDTAPGYVAG AHQFGLSQNS HLVLPLNQSD VRKRLQVQLS IRTFASSGLI
2770 2780 2790 2800 2810 2820
YYVAHQNQMD YATLQLQEGR LHFMFDLGKG RTKVSHPALL SDGKWHTVKT EYIKRKAFMT
2830 2840 2850 2860 2870 2880
VDGQESPSVT VVGNATTLDV ERKLYLGGLP SHYRARNIGT ITHSIPACIG EIMVNGQQLD
2890 2900 2910 2920 2930 2940
KDRPLSASAV DRCYVVAQEG TFFEGSGYAA LVKEGYKVRL DLNITLEFRT TSKNGVLLGI
2950 2960 2970 2980 2990 3000
SSAKVDAIGL EIVDGKVLFH VNNGAGRITA TYQPRAARAL CDGKWHTLQA HKSKHRIVLT
3010 3020 3030 3040 3050 3060
VDGNSVRAES PHTHSTSADT NDPIYVGGYP AHIKQNCLSS RASFRGCVRN LRLSRGSQVQ
3070 3080
SLDLSRAFDL QGVFPHSCPG PEP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P19137-25-Pyrrolidone carboxylic acid | QQRGLF... | 25 | pyrrolidone carboxylic acid- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P19137-1890-unknown | GALDRD... | 1890 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32187 | |||
P19137-2223-unknown | SVKEAS... | 2223 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33425 | |||
P19137-2374-unknown | VDLGSG... | 2374 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32188 | |||
P19137-2584-unknown | YSDGQE... | 2584 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34623 | |||
P19137-2584-unknown | YSDGQE... | 2584 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33426 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LQSRAG | 1889 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32187 | |||
...NMGSLS | 2222 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33425 | |||
...RVKVMV | 2373 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32188 | |||
...APTGSY | 2583 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34623 | |||
...APTGSY | 2583 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33426 | |||
...GPEP | 3084 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
ELNE_MOUSE | 1889 | SRAG.|.GALD | inferred from experiment | unknown | MEROPS | Merops ELNE_MOUSE -> LAMA1_MOUSE @1889 | ||
MMP2_MOUSE | 2222 | GSLS.|.SVKE | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> LAMA1_MOUSE @2222 | ||
ELNE_MOUSE | 2373 | KVMV.|.VDLG | inferred from experiment | unknown | MEROPS | Merops ELNE_MOUSE -> LAMA1_MOUSE @2373 | ||
MMP9_MOUSE | 2583 | TGSY.|.YSDG | inferred from experiment | unknown | MEROPS | Merops MMP9_MOUSE -> LAMA1_MOUSE @2583 | ||
MMP2_MOUSE | 2583 | TGSY.|.YSDG | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> LAMA1_MOUSE @2583 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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