TopFIND 4.0

P20029: Endoplasmic reticulum chaperone BiP {ECO:0000305}

General Information

Protein names
- Endoplasmic reticulum chaperone BiP {ECO:0000305}
- 3.6.4.10 {ECO:0000250|UniProtKB:P11021}
- 78 kDa glucose-regulated protein {ECO:0000303|PubMed:7607546}
- GRP-78 {ECO:0000303|PubMed:7607546}
- Binding-immunoglobulin protein {ECO:0000303|PubMed:2895472}
- BiP {ECO:0000303|PubMed:2895472}
- Heat shock protein 70 family protein 5 {ECO:0000305}
- HSP70 family protein 5 {ECO:0000305}
- Heat shock protein family A member 5 {ECO:0000312|MGI:MGI:95835}
- Immunoglobulin heavy chain-binding protein {ECO:0000303|PubMed:2895472}
Gene names Hspa5
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P20029

17

N-termini

13

C-termini

14

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MMKFTVVAAA LLLLGAVRAE EEDKKEDVGT VVGIDLGTTY SCVGVFKNGR VEIIANDQGN 
        70         80         90        100        110        120 
RITPSYVAFT PEGERLIGDA AKNQLTSNPE NTVFDAKRLI GRTWNDPSVQ QDIKFLPFKV 
       130        140        150        160        170        180 
VEKKTKPYIQ VDIGGGQTKT FAPEEISAMV LTKMKETAEA YLGKKVTHAV VTVPAYFNDA 
       190        200        210        220        230        240 
QRQATKDAGT IAGLNVMRII NEPTAAAIAY GLDKREGEKN ILVFDLGGGT FDVSLLTIDN 
       250        260        270        280        290        300 
GVFEVVATNG DTHLGGEDFD QRVMEHFIKL YKKKTGKDVR KDNRAVQKLR REVEKAKRAL 
       310        320        330        340        350        360 
SSQHQARIEI ESFFEGEDFS ETLTRAKFEE LNMDLFRSTM KPVQKVLEDS DLKKSDIDEI 
       370        380        390        400        410        420 
VLVGGSTRIP KIQQLVKEFF NGKEPSRGIN PDEAVAYGAA VQAGVLSGDQ DTGDLVLLDV 
       430        440        450        460        470        480 
CPLTLGIETV GGVMTKLIPR NTVVPTKKSQ IFSTASDNQP TVTIKVYEGE RPLTKDNHLL 
       490        500        510        520        530        540 
GTFDLTGIPP APRGVPQIEV TFEIDVNGIL RVTAEDKGTG NKNKITITND QNRLTPEEIE 
       550        560        570        580        590        600 
RMVNDAEKFA EEDKKLKERI DTRNELESYA YSLKNQIGDK EKLGGKLSSE DKETMEKAVE 
       610        620        630        640        650    
EKIEWLESHQ DADIEDFKAK KKELEEIVQP IISKLYGSGG PPPTGEEDTS EKDEL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

17 N-termini - 13 C-termini - 14 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)