P22570: NADPH:adrenodoxin oxidoreductase, mitochondrial

General Information

Protein names	- NADPH:adrenodoxin oxidoreductase, mitochondrial - AR - Adrenodoxin reductase {ECO:0000303\|PubMed:2845396} - 1.18.1.6 {ECO:0000250\|UniProtKB:P08165} - Ferredoxin--NADP(+) reductase - Ferredoxin reductase
Gene names	FDXR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P22570

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Long of NADPH:adrenodoxin oxidoreductase, mitochondrial - Isoform 3 of NADPH:adrenodoxin oxidoreductase, mitochondrial - Isoform 4 of NADPH:adrenodoxin oxidoreductase, mitochondrial - Isoform 5 of NADPH:adrenodoxin oxidoreductase, mitochondrial - Isoform 6 of NADPH:adrenodoxin oxidoreductase, mitochondrial - Isoform 7 of NADPH:adrenodoxin oxidoreductase, mitochondrial

Sequence View

        10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H         10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H         10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H         10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H         10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H         10         20         30         40         50         60
MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH
        70         80         90        100        110        120
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP
       130        140        150        160        170        180
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV
       190        200        210        220        230        240
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE
       250        260        270        280        290        300
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS
       310        320        330        340        350        360
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI
       370        380        390        400        410        420
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM
       430        440        450        460        470        480
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV
       490
DPQEMLRLLG H

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P22570-1-unknown	MASRCW...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66416
P22570-1-unknown	MASRCW...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66417
P22570-1-unknown	MASRCW...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66419
P22570-1-unknown	MASRCW...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66420
P22570-1-unknown	MASRCW...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66421
P22570-33-unknown	STQEKT...	33	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P22570-33-unknown	STQEKT...	33	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115039
P22570-33-unknown	STQEKT...	33	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115040
P22570-33-unknown	STQEKT...	33	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115041
P22570-33-unknown	STQEKT...	33	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115042
P22570-33-	STQEKT...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLLGH	491	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62036
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62038
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62037
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62034
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62039
...RLLGH	491	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62035

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)