TopFIND 4.0

P23116: Eukaryotic translation initiation factor 3 subunit A {ECO:0000255|HAMAP-Rule:MF_03000}

General Information

Protein names
- Eukaryotic translation initiation factor 3 subunit A {ECO:0000255|HAMAP-Rule:MF_03000}
- eIF3a {ECO:0000255|HAMAP-Rule:MF_03000}
- Centrosomin
- Eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255|HAMAP-Rule:MF_03000}
- eIF-3-theta {ECO:0000255|HAMAP-Rule:MF_03000}
- eIF3 p167
- eIF3 p180
- eIF3 p185
- p162
Gene names Eif3a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P23116

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD 
        70         80         90        100        110        120 
LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKLAEEK TEAAKEESQQ MVLDIEDLDN 
       130        140        150        160        170        180 
IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ 
       190        200        210        220        230        240 
AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA 
       250        260        270        280        290        300 
ISMELWQEAF KAVEDIHGLF SLSKKPPKPQ LMANYYNKVS TVFWKSGNAL FHASTLHRLY 
       310        320        330        340        350        360 
HLSREMRKNL TQEEMQRMST RVLLATLSIP ITPERTDIAR LLDMDGIIVE KQRRLATLLG 
       370        380        390        400        410        420 
LQAPPTRIGL INDMVRFSVL QYVVPEVKDL YNWLEVEFNP LKLCERVTKV LNWVREQPEK 
       430        440        450        460        470        480 
EPELQQYVPQ LQNNTILRLL QQVAQIYQSI EFSRLTSLVP FVDAFQLERA IVDAARHCDL 
       490        500        510        520        530        540 
QVRIDHTSRT LSFGSDLNYA TREDAPVGPH LQSMPSEQIR NQLTAMSSVL AKALEVIRPA 
       550        560        570        580        590        600 
HILQEKEEQH QLAVNAYLKN SRKEHQRILA RRQTIEERKE RLESLNIQRE KEELEQREAE 
       610        620        630        640        650        660 
LQKVRKAEEE RLRQEAKERE KERILQEHEQ IKKKTVRERL EQIKKTELGA KAFKDIDIED 
       670        680        690        700        710        720 
LEELDPDFIM AKQVEQLEKE KKELQERLKN QEKKIDYFER AKRLEEIPLI KSAYEEQRVK 
       730        740        750        760        770        780 
DMDLWEQQEE ERITTMQLER EKALEHKNRM SRMLEDRDLF VMRLKAARQS VYEEKLKQFE 
       790        800        810        820        830        840 
ERLAEERHSR LEDRKRQRKE ERKITYYREK EEEEQRRAEE QMLKEREERE RAERAKREEE 
       850        860        870        880        890        900 
LREYQERVKK LEEVERKKRQ RELEIEERER RREEERRLGD DPLSRKDSRW GDRDSEGTWR 
       910        920        930        940        950        960 
KGPEADSEWR RGPPEKEWRR ETRDDERPHR RDEDRLRRLG GDDEERESSL RPDDDRIPRR 
       970        980        990       1000       1010       1020 
GLDDDRGPRR GPDEDRFSRR GTDDDRPSWR NADDDRPPRR IGDDDRGSWR HTDDDRPPRR 
      1030       1040       1050       1060       1070       1080 
GLDDERGSWR TADEDRGPRR GMDDDRGPRR GGADDERSSW RNADDDRGPR RGMDDDRGPR 
      1090       1100       1110       1120       1130       1140 
RGLDDDRGPW RNAAEDRISR RGADDDRGPW RNMDDDRVPR RGDDARPGPW RPFVKPGGWR 
      1150       1160       1170       1180       1190       1200 
EKEKAREESW GPPRESRPSE EREWDRDKEK DRDNQDREEN DKDLERDRDR ERDGDREDRF 
      1210       1220       1230       1240       1250       1260 
RRPRDEGGWR RGPAEESSSW RDSSRRDDRD REDRRRDRDD RRDLRDLRDR RDLRDDRDRR 
      1270       1280       1290       1300       1310       1320 
GPPLRSEREE ASSWRRTDDR KDDRTEERDP PRRVPPPALS RDRERERERE GEKEKASWRA 
      1330       1340    
EKDRESLRRT KNETDEDGWT TVRR

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)