TopFIND 4.0

P23979: 5-hydroxytryptamine receptor 3A

General Information

Protein names
- 5-hydroxytryptamine receptor 3A
- 5-HT3-A
- 5-HT3A
- 5-hydroxytryptamine receptor 3
- 5-HT-3
- 5-HT3R
- Serotonin receptor 3A
- Serotonin-gated ion channel receptor
Gene names Htr3a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P23979

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLCIPQVLL ALFLSMLTAP GEGSRRRATQ EDTTQPALLR LSDHLLANYK KGVRPVRDWR 
        70         80         90        100        110        120 
KPTTVSIDVI MYAILNVDEK NQVLTTYIWY RQYWTDEFLQ WTPEDFDNVT KLSIPTDSIW 
       130        140        150        160        170        180 
VPDILINEFV DVGKSPNIPY VYVHHRGEVQ NYKPLQLVTA CSLDIYNFPF DVQNCSLTFT 
       190        200        210        220        230        240 
SWLHTIQDIN ITLWRSPEEV RSDKSIFINQ GEWELLEVFP QFKEFSIDIS NSYAEMKFYV 
       250        260        270        280        290        300 
IIRRRPLFYA VSLLLPSIFL MVVDIVGFCL PPDSGERVSF KITLLLGYSV FLIIVSDTLP 
       310        320        330        340        350        360 
ATIGTPLIGV YFVVCMALLV ISLAETIFIV RLVHKQDLQR PVPDWLRHLV LDRIAWILCL 
       370        380        390        400        410        420 
GEQPMAHRPP ATFQANKTDD CSGSDLLPAM GNHCSHVGGP QDLEKTPRGR GSPLPPPREA 
       430        440        450        460        470        480 
SLAVRGLLQE LSSIRHFLEK RDEMREVARD WLRVGYVLDR LLFRIYLLAV LAYSITLVTL 
   
WSIWHYS

Isoforms

- Isoform 5-HT3R-AS of 5-hydroxytryptamine receptor 3A

Sequence View

        10         20         30         40         50         60 
MRLCIPQVLL ALFLSMLTAP GEGSRRRATQ EDTTQPALLR LSDHLLANYK KGVRPVRDWR 
        70         80         90        100        110        120 
KPTTVSIDVI MYAILNVDEK NQVLTTYIWY RQYWTDEFLQ WTPEDFDNVT KLSIPTDSIW 
       130        140        150        160        170        180 
VPDILINEFV DVGKSPNIPY VYVHHRGEVQ NYKPLQLVTA CSLDIYNFPF DVQNCSLTFT 
       190        200        210        220        230        240 
SWLHTIQDIN ITLWRSPEEV RSDKSIFINQ GEWELLEVFP QFKEFSIDIS NSYAEMKFYV 
       250        260        270        280        290        300 
IIRRRPLFYA VSLLLPSIFL MVVDIVGFCL PPDSGERVSF KITLLLGYSV FLIIVSDTLP 
       310        320        330        340        350        360 
ATIGTPLIGV YFVVCMALLV ISLAETIFIV RLVHKQDLQR PVPDWLRHLV LDRIAWILCL 
       370        380        390        400        410        420 
GEQPMAHRPP ATFQANKTDD CSGSDLLPAM GNHCSHVGGP QDLEKTPRGR GSPLPPPREA 
       430        440        450        460        470        480 
SLAVRGLLQE LSSIRHFLEK RDEMREVARD WLRVGYVLDR LLFRIYLLAV LAYSITLVTL 
   
WSIWHYS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IWHYS 487 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IWHYS 487 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61413

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)