P24001: Interleukin-32
Protein names | - Interleukin-32 - IL-32 - Natural killer cells protein 4 - Tumor necrosis factor alpha-inducing factor |
---|---|
Gene names | IL32 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P24001 |
4
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
Isoforms
- Isoform 2 of Interleukin-32 - Isoform 3 of Interleukin-32 - Isoform 4 of Interleukin-32 - Isoform 5 of Interleukin-32 - Isoform 6 of Interleukin-32 - Isoform 7 of Interleukin-32Sequence View
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
10 20 30 40 50 60
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC
70 80 90 100 110 120
LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE
130 140 150 160 170 180
KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV
190 200 210 220 230
VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
Protein Neighborhood
Domains & Features
4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P24001-31-unknown | AWVSAC... | 31 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27780 | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138183 | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139012 | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139746 | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139747 | |||
P24001-104-unknown | VAAYYE... | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt195848 | |||
P24001-106-unknown | AYYEEQ... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167808 | |||
P24001-106-unknown | AYYEEQ... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167810 | |||
P24001-106-unknown | AYYEEQ... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167807 | |||
P24001-106-unknown | AYYEEQ... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167809 | |||
P24001-106-unknown | AYYEEQ... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167811 | |||
P24001-106- | AYYEEQ... | 106 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P24001-106- | AYYEEQ... | 106 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P24001-106- | AYYEEQ... | 106 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GYLETV | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27780 | |||
...GYLETV | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122081 | |||
...GYLETV | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122845 | |||
...GYLETV | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122846 | |||
...PQSSK | 234 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73389 | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73392 | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73390 | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73388 | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73391 | |||
...PQSSK | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73387 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
PRTN3_HUMAN | 103 | LETV.|.VAAY | inferred from experiment | unknown | MEROPS | Kim SH | Novick D et al.:Proteinase 3 is an IL-32 bindin... (S01.134) | 16488976, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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