P24547: Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}

General Information

Protein names	- Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156} - IMP dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156} - IMPD 2 {ECO:0000255\|HAMAP-Rule:MF_03156} - IMPDH 2 {ECO:0000255\|HAMAP-Rule:MF_03156} - 1.1.1.205 {ECO:0000255\|HAMAP-Rule:MF_03156} - IMPDH-II
Gene names	Impdh2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P24547

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD LTSALTKKIT
        70         80         90        100        110        120
LKTPLVSSPM DTVTEAGMAI AMALTGGIGF IHHNCTPEFQ ANEVRKVKKY EQGFITDPVV
       130        140        150        160        170        180
LSPKDRVRDV FEAKARHGFC GIPITDTGRM GSRLVGIISS RDIDFLKEEE HDRFLEEIMT
       190        200        210        220        230        240
KREDLVVAPA GVTLKEANEI LQRSKKGKLP IVNENDELVA IIARTDLKKN RDYPLASKDA
       250        260        270        280        290        300
KKQLLCGAAI GTHEDDKYRL DLLALAGVDV VVLDSSQGNS IFQINMIKYI KEKYPSLQVI
       310        320        330        340        350        360
GGNVVTAAQA KNLIDAGVDA LRVGMGSGSI CITQEVLACG RPQATAVYKV SEYARRFGVP
       370        380        390        400        410        420
VIADGGIQNV GHIAKALALG ASTVMMGSLL AATTEAPGEY FFSDGIRLKK YRGMGSLDAM
       430        440        450        460        470        480
DKHLSSQNRY FSEADKIKVA QGVSGAVQDK GSIHKFVPYL IAGIQHSCQD IGAKSLTQVR
       490        500        510
AMMYSGELKF EKRTSSAQVE GGVHSLHSYE KRLF

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P24547-2-unknown	ADYLIS...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P24547-2-unknown	ADYLIS...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P24547-63-unknown	TPLVSS...	63	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P24547-171-unknown	HDRFLE...	171	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P24547-247-unmodified	GAAIGT...	247		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P24547-313-unknown	LIDAGV...	313	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33467

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AQAKNL	312	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33467
	...EKRLF	514	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	312	AKNL.\|.LIDA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)