P26043: Radixin

General Information

Protein names	- Radixin - ESP10
Gene names	Rdx
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P26043

9 N-termini

8 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTVGLR EVWFFGLQYV DSKGYSTWLK
        70         80         90        100        110        120
LNKKVTQQDV KKENPLQFKF RAKFFPEDVS EELIQEITQR LFFLQVKEAI LNDEIYCPPE
       130        140        150        160        170        180
TAVLLASYAV QAKYGDYNKE IHKPGYLAND RLLPQRVLEQ HKLTKEQWEE RIQNWHEEHR
       190        200        210        220        230        240
GMLREDSMME YLKIAQDLEM YGVNYFEIKN KKGTELWLGV DALGLNIYEH DDKLTPKIGF
       250        260        270        280        290        300
PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI
       310        320        330        340        350        360
EVQQMKAQAR EEKHQKQLER AQLENEKKKR EIAEKEKERI EREKEELMER LRQIEEQTVK
       370        380        390        400        410        420
AQKELEEQTR KALELEQERQ RAKEEAERLD RERRAAEEAK SAIAKQAADQ MKNQEQLAAE
       430        440        450        460        470        480
LAEFTAKIAL LEEAKKKKEE EATEWQHKAF AAQEDLEKTK EELKTVMSAP PPPPPPPVIP
       490        500        510        520        530        540
PTENEHDEQD ENSAEASAEL SSEGVMNHRS EEERVTETQK NERVKKQLQA LSSELAQARD
       550        560        570        580
ETKKTQNDVL HAENVKAGRD KYKTLRQIRQ GNTKQRIDEF EAM

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 8 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P26043-1-unknown	MPKPIN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P26043-85-unknown	FPEDVS...	85	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P26043-262-unknown	KKAPDF...	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33486
P26043-263-unknown	KAPDFV...	263	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33487
P26043-264-unknown	APDFVF...	264	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33488
P26043-302-unknown	VQQMKA...	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29881
P26043-323-unknown	LENEKK...	323	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29882
P26043-500-unknown	LSSEGV...	500	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33489
P26043-531-unknown	LSSELA...	531	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33490

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IKPIDK	261	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33486
...KPIDKK	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33487
...PIDKKA	263	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33488
...PDTIEV	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29881
...LERAQL	322	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29882
...EASAEL	499	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33489
...KQLQAL	530	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33490
...EFEAM	583	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	261	PIDK.\|.KKAP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	262	IDKK.\|.KAPD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	263	DKKA.\|.APDF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	301	TIEV.\|.VQQM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RADI_MOUSE @301
CATE_MOUSE	322	RAQL.\|.LENE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RADI_MOUSE @322
MMP2_MOUSE	499	SAEL.\|.LSSE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	530	LQAL.\|.LSSE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)