P26638: Serine--tRNA ligase, cytoplasmic

General Information

Protein names	- Serine--tRNA ligase, cytoplasmic - 6.1.1.11 {ECO:0000250\|UniProtKB:P49591} - Seryl-tRNA synthetase - SerRS - Seryl-tRNA(Ser/Sec) synthetase
Gene names	Sars
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P26638

4 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVLDLDLFRV DKGGDPALIR ETQEKRFKDP GLVDQLVKAD SEWRRCRFRA DNLNKLKNLC
        70         80         90        100        110        120
SKTIGEKMKK KEAVGDDESV PENVLNFDDL TADALAALKV SQIKKVRLLI DEAIQKCDGE
       130        140        150        160        170        180
RVKLEAERFE NLREIGNLLH PSVPISNDED ADNKVERIWG DCTVRKKYSH VDLVVMVDGF
       190        200        210        220        230        240
EGEKGAVVAG SRGYFLKGPL VFLEQALIQY ALRTLGSRGY TPIYTPFFMR KEVMQEVAQL
       250        260        270        280        290        300
SQFDEELYKV IGKGSEKSDD NSYDEKYLIA TSEQPIAALH RDEWLRPEDL PIKYAGLSTC
       310        320        330        340        350        360
FRQEVGSHGR DTRGIFRVHQ FEKIEQFVYS SPHDNKSWEM FDEMIATAEE FYQSLGIPYH
       370        380        390        400        410        420
IVNIVSGSLN HAASKKLDLE AWFPGSGAFR ELVSCSNCTD YQARRLRIRY GQTKKMMDKV
       430        440        450        460        470        480
EFVHMLNATM CATTRTICAI LENYQAEKGI AVPEKLREFM PPGLQELIPF VKPAPIDQEP
       490        500        510
SKKQKKQHEG SKKKAKEVPL ENQLQSMEVT EA

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P26638-1-Acetylation	MVLDLD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P26638-96-unknown	AALKVS...	96		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28845
P26638-96-unknown	AALKVS...	96		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29885
P26638-99-unknown	KVSQIK...	99		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28846
P26638-172-unknown	DLVVMV...	172		inferred from electronic annotation	unknown	TISdb	inferred from TISdb

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TADALA	95	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28845
...TADALA	95	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29885
...ALAALK	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28846
...DEWLRP	286	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118676
...SNCTDY	400	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120879
...EVTEA	512	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATD_MOUSE	95	DALA.\|.AALK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> SYSC_MOUSE @95
CATE_MOUSE	95	DALA.\|.AALK	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SYSC_MOUSE @95
CATD_MOUSE	98	AALK.\|.KVSQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> SYSC_MOUSE @98

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)