TopFIND 4.0

P27046: Alpha-mannosidase 2

General Information

Protein names
- Alpha-mannosidase 2
- 3.2.1.114 {ECO:0000250|UniProtKB:P28494}
- Golgi alpha-mannosidase II
- AMan II
- Man II
- Mannosidase alpha class 2A member 1
- Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
Gene names Man2a1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P27046

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLSRQFTVF GSAIFCVVIF SLYLMLDRGH LDYPRGPRQE GSFPQGQLSI LQEKIDHLER 
        70         80         90        100        110        120 
LLAENNEIIS NIRDSVINLS ESVEDGPRGS PGNASQGSIH LHSPQLALQA DPRDCLFASQ 
       130        140        150        160        170        180 
SGSQPRDVQM LDVYDLIPFD NPDGGVWKQG FDIKYEADEW DHEPLQVFVV PHSHNDPGWL 
       190        200        210        220        230        240 
KTFNDYFRDK TQYIFNNMVL KLKEDSSRKF MWSEISYLAK WWDIIDIPKK EAVKSLLQNG 
       250        260        270        280        290        300 
QLEIVTGGWV MPDEATPHYF ALIDQLIEGH QWLEKNLGVK PRSGWAIDPF GHSPTMAYLL 
       310        320        330        340        350        360 
KRAGFSHMLI QRVHYAIKKH FSLHKTLEFF WRQNWDLGSA TDILCHMMPF YSYDIPHTCG 
       370        380        390        400        410        420 
PDPKICCQFD FKRLPGGRYG CPWGVPPEAI SPGNVQSRAQ MLLDQYRKKS KLFRTKVLLA 
       430        440        450        460        470        480 
PLGDDFRFSE YTEWDLQCRN YEQLFSYMNS QPHLKVKIQF GTLSDYFDAL EKAVAAEKKS 
       490        500        510        520        530        540 
SQSVFPALSG DFFTYADRDD HYWSGYFTSR PFYKRMDRIM ESRIRAAEIL YQLALKQAQK 
       550        560        570        580        590        600 
YKINKFLSSP HYTTLTEARR NLGLFQHHDA ITGTAKDWVV VDYGTRLFQS LNSLEKIIGD 
       610        620        630        640        650        660 
SAFLLILKDK KLYQSDPSKA FLEMDTKQSS QDSLPQKIII QLSAQEPRYL VVYNPFEQER 
       670        680        690        700        710        720 
HSVVSIRVNS ATVKVLSDSG KPVEVQVSAV WNDMRTISQA AYEVSFLAHI PPLGLKVFKI 
       730        740        750        760        770        780 
LESQSSSSHL ADYVLYNNDG LAENGIFHVK NMVDAGDAIT IENPFLAIWF DRSGLMEKVR 
       790        800        810        820        830        840 
RKEDSRQHEL KVQFLWYGTT NKRDKSGAYL FLPDGQGQPY VSLRPPFVRV TRGRIYSDVT 
       850        860        870        880        890        900 
CFLEHVTHKV RLYNIQGIEG QSMEVSNIVN IRNVHNREIV MRISSKINNQ NRYYTDLNGY 
       910        920        930        940        950        960 
QIQPRRTMSK LPLQANVYPM CTMAYIQDAE HRLTLLSAQS LGASSMASGQ IEVFMDRRLM 
       970        980        990       1000       1010       1020 
QDDNRGLGQG VHDNKITANL FRILLEKRSA VNMEEEKKSP VSYPSLLSHM TSSFLNHPFL 
      1030       1040       1050       1060       1070       1080 
PMVLSGQLPS PAFELLSEFP LLQSSLPCDI HLVNLRTIQS KMGKGYSDEA ALILHRKGFD 
      1090       1100       1110       1120       1130       1140 
CQFSSRGIGL PCSTTQGKMS VLKLFNKFAV ESLVPSSLSL MHSPPDAQNM SEVSLSPMEI 
      1150    
STFRIRLRWT 

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)