P28653: Biglycan

General Information

Protein names	- Biglycan - Bone/cartilage proteoglycan I - PG-S1
Gene names	Bgn
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P28653

5 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCPLWLLTLL LALSQALPFE QKGFWDFTLD DGLLMMNDEE ASGSDTTSGV PDLDSVTPTF
        70         80         90        100        110        120
SAMCPFGCHC HLRVVQCSDL GLKTVPKEIS PDTTLLDLQN NDISELRKDD FKGLQHLYAL
       130        140        150        160        170        180
VLVNNKISKI HEKAFSPLRK LQKLYISKNH LVEIPPNLPS SLVELRIHDN RIRKVPKGVF
       190        200        210        220        230        240
SGLRNMNCIE MGGNPLENSG FEPGAFDGLK LNYLRISEAK LTGIPKDLPE TLNELHLDHN
       250        260        270        280        290        300
KIQAIELEDL LRYSKLYRLG LGHNQIRMIE NGSLSFLPTL RELHLDNNKL SRVPAGLPDL
       310        320        330        340        350        360
KLLQVVYLHS NNITKVGIND FCPMGFGVKR AYYNGISLFN NPVPYWEVQP ATFRCVTDRL

AIQFGNYKK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P28653-20-unknown	EQKGFW...	20	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P28653-38-unknown	DEEASG...	38	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P28653-38-unknown	DEEASG...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28310
P28653-221-unknown	LTGIPK...	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33503
P28653-242-unknown	IQAIEL...	242	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33504
P28653-345-unknown	YWEVQP...	345	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33505

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLMMND	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28310
...ISEAKL	220	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33503
...LDHNKI	241	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33504
...NNPVPY	344	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33505
...GNYKK	369	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
BMP1_MOUSE	37	MMND.\|.DEEA	inferred from experiment	unknown	MEROPS	Greenspan DS	Scott IC et al.:Bone morphogenetic protein-1 pr... (M12.005)	10896944,
MMP2_MOUSE	220	EAKL.\|.LTGI	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> PGS1_MOUSE @220
MMP2_MOUSE	241	HNKI.\|.IQAI	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> PGS1_MOUSE @241
MMP2_MOUSE	344	PVPY.\|.YWEV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> PGS1_MOUSE @344

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)