P29965: CD40 ligand

General Information

Protein names	- CD40 ligand - CD40-L - T-cell antigen Gp39 - TNF-related activation protein - TRAP - Tumor necrosis factor ligand superfamily member 5 - CD154 - CD40 ligand, membrane form - CD40 ligand, soluble form
Gene names	CD40LG
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P29965

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MIETYNQTSP RSAATGLPIS MKIFMYLLTV FLITQMIGSA LFAVYLHRRL DKIEDERNLH
        70         80         90        100        110        120
EDFVFMKTIQ RCNTGERSLS LLNCEEIKSQ FEGFVKDIML NKEETKKENS FEMQKGDQNP
       130        140        150        160        170        180
QIAAHVISEA SSKTTSVLQW AEKGYYTMSN NLVTLENGKQ LTVKRQGLYY IYAQVTFCSN
       190        200        210        220        230        240
REASSQAPFI ASLCLKSPGR FERILLRAAN THSSAKPCGQ QSIHLGGVFE LQPGASVFVN
       250        260
VTDPSQVSHG TGFTSFGLLK L

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P29965-1-	MIETYN...	1		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P29965-1-unknown	MIETYN...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P29965-1-unknown	MIETYN...	1		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P29965-113-unknown	MQKGDQ...	113	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P29965-114-unknown	QKGDQN...	114	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC98

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NSFEMQ	113	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC98
	...GLLKL	261	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ADA10_HUMAN	113	FEMQ.\|.QKGD	inferred from experiment	unknown	MEROPS	Murphy G	Amour A et al.:The enzymatic activity of ADAM8... (M12.210)	12135759,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)