P30416: Peptidyl-prolyl cis-trans isomerase FKBP4

General Information

Protein names	- Peptidyl-prolyl cis-trans isomerase FKBP4 - PPIase FKBP4 - 5.2.1.8 - 52 kDa FK506-binding protein - 52 kDa FKBP - FKBP-52 - 59 kDa immunophilin - p59 - FK506-binding protein 4 - FKBP-4 - FKBP59 - HSP-binding immunophilin - HBI - Immunophilin FKBP52 - Rotamase - Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed
Gene names	Fkbp4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P30416

9 N-termini

8 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTAEEMKAAE NGAQSAPLPL EGVDISPKQD EGVLKVIKRE GTGTETPMIG DRVFVHYTGW
        70         80         90        100        110        120
LLDGTKFDSS LDRKDKFSFD LGKGEVIKAW DIAVATMKVG EVCHITCKPE YAYGAAGSPP
       130        140        150        160        170        180
KIPPNATLVF EVELFEFKGE DLTEEEDGGI IRRIRTRGEG YARPNDGAMV EVALEGYHKD
       190        200        210        220        230        240
RLFDQRELCF EVGEGESLDL PCGLEEAIQR MEKGEHSIVY LKPSYAFGSV GKERFQIPPH
       250        260        270        280        290        300
AELRYEVRLK SFEKAKESWE MSSAEKLEQS NIVKERGTAY FKEGKYKQAL LQYKKIVSWL
       310        320        330        340        350        360
EYESSFSGEE MQKVHALRLA SHLNLAMCHL KLQAFSAAIE SCNKALELDS NNEKGLFRRG
       370        380        390        400        410        420
EAHLAVNDFD LARADFQKVL QLYPSNKAAK TQLAVCQQRT RRQLAREKKL YANMFERLAE
       430        440        450
EEHKVKAEVA AGDHPTDAEM KGERNNVAEN QSRVETEA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 8 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P30416-1-Acetylation	MTAEEM...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30416-2-Acetylation	TAEEMK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30416-2-Acetylation	TAEEMK...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P30416-20-unknown	LEGVDI...	20		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33518
P30416-23-unknown	VDISPK...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29919
P30416-61-unknown	LLDGTK...	61		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33519
P30416-147-unknown	DGGIIR...	147		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P30416-339-unknown	IESCNK...	339		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33520
P30416-359-unmodified	RGEAHL...	359			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P30416-364-unknown	LAVNDF...	364		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33521

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SAPLPL	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33518
...LPLEGV	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29919
...HYTGWL	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33519
...VGKERF	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122087
...ESSFSG	307	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119930
...AFSAAI	338	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33520
...RGEAHL	363	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33521
...VETEA	458	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	19	PLPL.\|.LEGV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	22	LEGV.\|.VDIS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> FKBP4_MOUSE @22
MMP2_MOUSE	60	TGWL.\|.LLDG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	338	SAAI.\|.IESC	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	363	EAHL.\|.LAVN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)