P30519: Heme oxygenase 2

General Information

Protein names	- Heme oxygenase 2 - HO-2 - 1.14.14.18 {ECO:0000250\|UniProtKB:O48782}
Gene names	HMOX2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P30519

5 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG
        70         80         90        100        110        120
NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN
       130        140        150        160        170        180
WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST
       190        200        210        220        230        240
GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA
       250        260        270        280        290        300
GSTLARETLE DGFPVHDGKG DMRKCPFYAA EQDKGALEGS SCPFRTAMAV LRKPSLQFIL
       310
AAGVALAAGL LAWYYM

Isoforms

- Isoform 2 of Heme oxygenase 2

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P30519-2-unknown	MSAEVE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30519-2-Acetylation	SAEVET...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30519-2-Acetylation	SAEVET...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P30519-2-Acetylation	SAEVET...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P30519-30-unknown	MADLSE...	30		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000460926
P30519-252-unknown	GFPVHD...	252			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P30519-252-	GFPVHD...	252			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P30519-252-	GFPVHD...	252			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P30519-252-	GFPVHD...	252			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P30519-252-	GFPVHD...	252			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P30519-252-	GFPVHD...	252			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KEALTK	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459445
...QCPKAA	130	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461428
...CPKAAQ	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458824
...PKAAQK	132	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460992
...KAFEYN	229	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458592
...FNELDQ	238	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458797
...AWYYM	316	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)