P32004: Neural cell adhesion molecule L1

General Information

Protein names	- Neural cell adhesion molecule L1 - N-CAM-L1 - NCAM-L1 - CD171
Gene names	L1CAM
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P32004

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVVALRYVWP LLLCSPCLLI QIPEEYEGHH VMEPPVITEQ SPRRLVVFPT DDISLKCEAS
        70         80         90        100        110        120
GKPEVQFRWT RDGVHFKPKE ELGVTVYQSP HSGSFTITGN NSNFAQRFQG IYRCFASNKL
       130        140        150        160        170        180
GTAMSHEIRL MAEGAPKWPK ETVKPVEVEE GESVVLPCNP PPSAEPLRIY WMNSKILHIK
       190        200        210        220        230        240
QDERVTMGQN GNLYFANVLT SDNHSDYICH AHFPGTRTII QKEPIDLRVK ATNSMIDRKP
       250        260        270        280        290        300
RLLFPTNSSS HLVALQGQPL VLECIAEGFP TPTIKWLRPS GPMPADRVTY QNHNKTLQLL
       310        320        330        340        350        360
KVGEEDDGEY RCLAENSLGS ARHAYYVTVE AAPYWLHKPQ SHLYGPGETA RLDCQVQGRP
       370        380        390        400        410        420
QPEVTWRING IPVEELAKDQ KYRIQRGALI LSNVQPSDTM VTQCEARNRH GLLLANAYIY
       430        440        450        460        470        480
VVQLPAKILT ADNQTYMAVQ GSTAYLLCKA FGAPVPSVQW LDEDGTTVLQ DERFFPYANG
       490        500        510        520        530        540
TLGIRDLQAN DTGRYFCLAA NDQNNVTIMA NLKVKDATQI TQGPRSTIEK KGSRVTFTCQ
       550        560        570        580        590        600
ASFDPSLQPS ITWRGDGRDL QELGDSDKYF IEDGRLVIHS LDYSDQGNYS CVASTELDVV
       610        620        630        640        650        660
ESRAQLLVVG SPGPVPRLVL SDLHLLTQSQ VRVSWSPAED HNAPIEKYDI EFEDKEMAPE
       670        680        690        700        710        720
KWYSLGKVPG NQTSTTLKLS PYVHYTFRVT AINKYGPGEP SPVSETVVTP EAAPEKNPVD
       730        740        750        760        770        780
VKGEGNETTN MVITWKPLRW MDWNAPQVQY RVQWRPQGTR GPWQEQIVSD PFLVVSNTST
       790        800        810        820        830        840
FVPYEIKVQA VNSQGKGPEP QVTIGYSGED YPQAIPELEG IEILNSSAVL VKWRPVDLAQ
       850        860        870        880        890        900
VKGHLRGYNV TYWREGSQRK HSKRHIHKDH VVVPANTTSV ILSGLRPYSS YHLEVQAFNG
       910        920        930        940        950        960
RGSGPASEFT FSTPEGVPGH PEALHLECQS NTSLLLRWQP PLSHNGVLTG YVLSYHPLDE
       970        980        990       1000       1010       1020
GGKGQLSFNL RDPELRTHNL TDLSPHLRYR FQLQATTKEG PGEAIVREGG TMALSGISDF
      1030       1040       1050       1060       1070       1080
GNISATAGEN YSVVSWVPKE GQCNFRFHIL FKALGEEKGG ASLSPQYVSY NQSSYTQWDL
      1090       1100       1110       1120       1130       1140
QPDTDYEIHL FKERMFRHQM AVKTNGTGRV RLPPAGFATE GWFIGFVSAI ILLLLVLLIL
      1150       1160       1170       1180       1190       1200
CFIKRSKGGK YSVKDKEDTQ VDSEARPMKD ETFGEYRSLE SDNEEKAFGS SQPSLNGDIK
      1210       1220       1230       1240       1250
PLGSDDSLAD YGGSVDVQFN EDGSFIGQYS GKKEKEAAGG NDSSGATSPI NPAVALE

Isoforms

- Isoform 2 of Neural cell adhesion molecule L1 - Isoform 3 of Neural cell adhesion molecule L1

Sequence View

        10         20         30         40         50         60
MVVALRYVWP LLLCSPCLLI QIPEEYEGHH VMEPPVITEQ SPRRLVVFPT DDISLKCEAS
        70         80         90        100        110        120
GKPEVQFRWT RDGVHFKPKE ELGVTVYQSP HSGSFTITGN NSNFAQRFQG IYRCFASNKL
       130        140        150        160        170        180
GTAMSHEIRL MAEGAPKWPK ETVKPVEVEE GESVVLPCNP PPSAEPLRIY WMNSKILHIK
       190        200        210        220        230        240
QDERVTMGQN GNLYFANVLT SDNHSDYICH AHFPGTRTII QKEPIDLRVK ATNSMIDRKP
       250        260        270        280        290        300
RLLFPTNSSS HLVALQGQPL VLECIAEGFP TPTIKWLRPS GPMPADRVTY QNHNKTLQLL
       310        320        330        340        350        360
KVGEEDDGEY RCLAENSLGS ARHAYYVTVE AAPYWLHKPQ SHLYGPGETA RLDCQVQGRP
       370        380        390        400        410        420
QPEVTWRING IPVEELAKDQ KYRIQRGALI LSNVQPSDTM VTQCEARNRH GLLLANAYIY
       430        440        450        460        470        480
VVQLPAKILT ADNQTYMAVQ GSTAYLLCKA FGAPVPSVQW LDEDGTTVLQ DERFFPYANG
       490        500        510        520        530        540
TLGIRDLQAN DTGRYFCLAA NDQNNVTIMA NLKVKDATQI TQGPRSTIEK KGSRVTFTCQ
       550        560        570        580        590        600
ASFDPSLQPS ITWRGDGRDL QELGDSDKYF IEDGRLVIHS LDYSDQGNYS CVASTELDVV
       610        620        630        640        650        660
ESRAQLLVVG SPGPVPRLVL SDLHLLTQSQ VRVSWSPAED HNAPIEKYDI EFEDKEMAPE
       670        680        690        700        710        720
KWYSLGKVPG NQTSTTLKLS PYVHYTFRVT AINKYGPGEP SPVSETVVTP EAAPEKNPVD
       730        740        750        760        770        780
VKGEGNETTN MVITWKPLRW MDWNAPQVQY RVQWRPQGTR GPWQEQIVSD PFLVVSNTST
       790        800        810        820        830        840
FVPYEIKVQA VNSQGKGPEP QVTIGYSGED YPQAIPELEG IEILNSSAVL VKWRPVDLAQ
       850        860        870        880        890        900
VKGHLRGYNV TYWREGSQRK HSKRHIHKDH VVVPANTTSV ILSGLRPYSS YHLEVQAFNG
       910        920        930        940        950        960
RGSGPASEFT FSTPEGVPGH PEALHLECQS NTSLLLRWQP PLSHNGVLTG YVLSYHPLDE
       970        980        990       1000       1010       1020
GGKGQLSFNL RDPELRTHNL TDLSPHLRYR FQLQATTKEG PGEAIVREGG TMALSGISDF
      1030       1040       1050       1060       1070       1080
GNISATAGEN YSVVSWVPKE GQCNFRFHIL FKALGEEKGG ASLSPQYVSY NQSSYTQWDL
      1090       1100       1110       1120       1130       1140
QPDTDYEIHL FKERMFRHQM AVKTNGTGRV RLPPAGFATE GWFIGFVSAI ILLLLVLLIL
      1150       1160       1170       1180       1190       1200
CFIKRSKGGK YSVKDKEDTQ VDSEARPMKD ETFGEYRSLE SDNEEKAFGS SQPSLNGDIK
      1210       1220       1230       1240       1250
PLGSDDSLAD YGGSVDVQFN EDGSFIGQYS GKKEKEAAGG NDSSGATSPI NPAVALE         10         20         30         40         50         60
MVVALRYVWP LLLCSPCLLI QIPEEYEGHH VMEPPVITEQ SPRRLVVFPT DDISLKCEAS
        70         80         90        100        110        120
GKPEVQFRWT RDGVHFKPKE ELGVTVYQSP HSGSFTITGN NSNFAQRFQG IYRCFASNKL
       130        140        150        160        170        180
GTAMSHEIRL MAEGAPKWPK ETVKPVEVEE GESVVLPCNP PPSAEPLRIY WMNSKILHIK
       190        200        210        220        230        240
QDERVTMGQN GNLYFANVLT SDNHSDYICH AHFPGTRTII QKEPIDLRVK ATNSMIDRKP
       250        260        270        280        290        300
RLLFPTNSSS HLVALQGQPL VLECIAEGFP TPTIKWLRPS GPMPADRVTY QNHNKTLQLL
       310        320        330        340        350        360
KVGEEDDGEY RCLAENSLGS ARHAYYVTVE AAPYWLHKPQ SHLYGPGETA RLDCQVQGRP
       370        380        390        400        410        420
QPEVTWRING IPVEELAKDQ KYRIQRGALI LSNVQPSDTM VTQCEARNRH GLLLANAYIY
       430        440        450        460        470        480
VVQLPAKILT ADNQTYMAVQ GSTAYLLCKA FGAPVPSVQW LDEDGTTVLQ DERFFPYANG
       490        500        510        520        530        540
TLGIRDLQAN DTGRYFCLAA NDQNNVTIMA NLKVKDATQI TQGPRSTIEK KGSRVTFTCQ
       550        560        570        580        590        600
ASFDPSLQPS ITWRGDGRDL QELGDSDKYF IEDGRLVIHS LDYSDQGNYS CVASTELDVV
       610        620        630        640        650        660
ESRAQLLVVG SPGPVPRLVL SDLHLLTQSQ VRVSWSPAED HNAPIEKYDI EFEDKEMAPE
       670        680        690        700        710        720
KWYSLGKVPG NQTSTTLKLS PYVHYTFRVT AINKYGPGEP SPVSETVVTP EAAPEKNPVD
       730        740        750        760        770        780
VKGEGNETTN MVITWKPLRW MDWNAPQVQY RVQWRPQGTR GPWQEQIVSD PFLVVSNTST
       790        800        810        820        830        840
FVPYEIKVQA VNSQGKGPEP QVTIGYSGED YPQAIPELEG IEILNSSAVL VKWRPVDLAQ
       850        860        870        880        890        900
VKGHLRGYNV TYWREGSQRK HSKRHIHKDH VVVPANTTSV ILSGLRPYSS YHLEVQAFNG
       910        920        930        940        950        960
RGSGPASEFT FSTPEGVPGH PEALHLECQS NTSLLLRWQP PLSHNGVLTG YVLSYHPLDE
       970        980        990       1000       1010       1020
GGKGQLSFNL RDPELRTHNL TDLSPHLRYR FQLQATTKEG PGEAIVREGG TMALSGISDF
      1030       1040       1050       1060       1070       1080
GNISATAGEN YSVVSWVPKE GQCNFRFHIL FKALGEEKGG ASLSPQYVSY NQSSYTQWDL
      1090       1100       1110       1120       1130       1140
QPDTDYEIHL FKERMFRHQM AVKTNGTGRV RLPPAGFATE GWFIGFVSAI ILLLLVLLIL
      1150       1160       1170       1180       1190       1200
CFIKRSKGGK YSVKDKEDTQ VDSEARPMKD ETFGEYRSLE SDNEEKAFGS SQPSLNGDIK
      1210       1220       1230       1240       1250
PLGSDDSLAD YGGSVDVQFN EDGSFIGQYS GKKEKEAAGG NDSSGATSPI NPAVALE

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P32004-1-unknown	MVVALR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79309
P32004-1-unknown	MVVALR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79310
P32004-20-unknown	IQIPEE...	20	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P32004-20-unknown	IQIPEE...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112302
P32004-861-unknown	HSKRHI...	861	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27581
P32004-861-unknown	HSKRHI...	861	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156701
P32004-861-unknown	HSKRHI...	861	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156716
P32004-864-unknown	RHIHKD...	864	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27584
P32004-864-unknown	RHIHKD...	864	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156707
P32004-864-unknown	RHIHKD...	864	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156725

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GSQRKH	860	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27581
...GSQRKH	860	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140188
...GSQRKH	860	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140204
...RKHSKR	863	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27584
...RKHSKR	863	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140195
...RKHSKR	863	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140213
...AVALE	1257	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AVALE	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74928
...AVALE	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74927

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
PLMN_HUMAN	860	QRKH.\|.HSKR	inferred from experiment	unknown	MEROPS	Montgomery AM	Nayeem N et al.:A potential role for the plasmi... (S01.233)	10574721,
PLMN_HUMAN	863	HSKR.\|.RHIH	inferred from experiment	unknown	MEROPS	Montgomery AM	Nayeem N et al.:A potential role for the plasmi... (S01.233)	10574721,

TopFIND

P32004: Neural cell adhesion molecule L1

General Information

4

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates