P35232: Prohibitin

General Information

Protein names	- Prohibitin
Gene names	PHB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35232

4 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV GEGTHFLIPW
        70         80         90        100        110        120
VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA SQLPRIFTSI GEDYDERVLP
       130        140        150        160        170        180
SITTEILKSV VARFDAGELI TQRELVSRQV SDDLTERAAT FGLILDDVSL THLTFGKEFT
       190        200        210        220        230        240
EAVEAKQVAQ QEAERARFVV EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK
       250        260        270
LEAAEDIAYQ LSRSRNITYL PAGQSVLLQL PQ

Isoforms

- Isoform 2 of Prohibitin

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P35232-1-unknown	MAAKVF...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P35232-1-unknown	MAAKVF...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85024
P35232-25-unknown	SALYNV...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174028
P35232-25-	SALYNV...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P35232-187-	QVAQQE...	187		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PSITTE	124	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000410680
...PSITTE	124	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt114145
...RFVVEK	201	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000407828
...FVVEKA	202	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000422182
...AIISAE	214	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000426433
...EAAEDI	246	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000393320
...LQLPQ	272	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LQLPQ	272		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LQLPQ	272		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)