P37889: Fibulin-2

General Information

Protein names	- Fibulin-2 - FIBL-2
Gene names	Fbln2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P37889

9 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLLQESAGVW LALALVTALT PSPSMAVPWQ DCTGAECPLL ENCIEEALEP GACCATCVQQ
        70         80         90        100        110        120
GCACEGYQYY DCVQGGFVDG RVPAGQSYFV DFGSTECSCP PGGGKISCQF MLCPELPPNC
       130        140        150        160        170        180
IEAVVVADSC PQCGQVGCVH SGRKYAAGHT VHLSSCRACH CPDAGGELIC YQLPGCHGNF
       190        200        210        220        230        240
SDAEEGDSER QYEDPYSYDQ EVAEAEATTA IVNEVQAGAE GPPAALGGGN LPPSSIRVTP
       250        260        270        280        290        300
WPVALPRPTA AAALGPPAPV QAKARRVTLD TEEDEEEEEE ETLVTEPPTA GSPGRLDSLP
       310        320        330        340        350        360
TRSPARPGFP VQEKEAEAKA GPEENLIPDA QVTPRSVMQE GAAPLPRSGL AALSPSLATD
       370        380        390        400        410        420
SSSEDPVKPS DHPTLSTLPP DRAQVSPSPE TPEEIPQHPQ LLPRFRAEED IDPNSVHSVP
       430        440        450        460        470        480
RGDLDGSTKD LIETCCAAGQ QWAIDNDECQ EIPENGAQSD ICRIAQRQCC ISYLKEKSCV
       490        500        510        520        530        540
AGVMGAKEGE TCGAEDNDTC GVSLYKQCCD CCGLGLRVRA EGQSCESNPN LGYPCNHVML
       550        560        570        580        590        600
SCCEGEEPLI VPEVRRPPEP EAAPRRVSEM EMASREALSL GTEAELPNSL PGDDQDECLM
       610        620        630        640        650        660
LPGELCQHLC INTVGSYRCA CFPGFELQGD GRTCRPDRGA PQLDTARESA PRSESAQVSP
       670        680        690        700        710        720
NTIPLPVPQP NTCKDNGPCR QVCRVVGDTA MCSCFPGYAI MADGVSCEDQ DECLMGTHDC
       730        740        750        760        770        780
SWKQFCVNTL GSFYCVNHTV LCAEGYILNA HRKCVDINEC VTDLHTCTRA EHCVNTPGSF
       790        800        810        820        830        840
QCYKALTCEP GYVLTDGECT DVDECVTGTH NCQAGFSCQN TKGSFYCQAR QRCMDGFLQD
       850        860        870        880        890        900
PEGNCVDINE CTSLLEPCRS GFSCINTVGS YTCQRNPLVC GRGYHANEEG SECVDVNECE
       910        920        930        940        950        960
TGVHRCGEGQ LCYNLPGSYR CDCKPGFQRD AFGRTCIDVN ECWVSPGRLC QHTCENTPGS
       970        980        990       1000       1010       1020
YRCSCAAGFL LAADGKHCED VNECETRRCS QECANIYGSY QCYCRQGYQL AEDGHTCTDI
      1030       1040       1050       1060       1070       1080
DECAQGAGIL CTFRCVNVPG SYQCACPEQG YTMMANGRSC KDLDECALGT HNCSEAETCH
      1090       1100       1110       1120       1130       1140
NIQGSFRCLR FDCPPNYVRV SETKCERTTC QDITECQTSP ARITHYQLNF QTGLLVPAHI
      1150       1160       1170       1180       1190       1200
FRIGPAPAFA GDTISLTITK GNEEGYFVTR RLNAYTGVVS LQRSVLEPRD FALDVEMKLW
      1210       1220
RQGSVTTFLA KMYIFFTTFA P

Isoforms

- Isoform 2 of Fibulin-2

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P37889-1-unknown	MLLQES...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74860
P37889-27-unknown	VPWQDC...	27	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P37889-27-unknown	VPWQDC...	27	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt114254
P37889-148-unknown	GHTVHL...	148	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P37889-148-unknown	GHTVHL...	148	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197616
P37889-173-unknown	LPGCHG...	173	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P37889-173-unknown	LPGCHG...	173	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197837
P37889-236-unknown	IRVTPW...	236	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34426
P37889-236-unknown	IRVTPW...	236	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147952
P37889-260-unknown	VQAKAR...	260	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34428
P37889-260-unknown	VQAKAR...	260	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148816
P37889-570-unknown	MEMASR...	570	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34430
P37889-570-unknown	MEMASR...	570	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt154217
P37889-963-5oxothiomorpholine-3-carboxylic-acid	CSCAAG...	963		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P37889-963-unknown	CSCAAG...	963	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160792

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPPSSI	235	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34426
...LPPSSI	235	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131313
...GPPAPV	259	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34428
...GPPAPV	259	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132192
...RRVSEM	569	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34430
...RRVSEM	569	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137638
...TTFAP	1221	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TTFAP	1221	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70478

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
MMP3_MOUSE	235	PSSI.\|.IRVT	inferred from experiment	unknown	MEROPS	Merops MMP3_MOUSE -> FBLN2_MOUSE @235
MMP3_MOUSE	259	PAPV.\|.VQAK	inferred from experiment	unknown	MEROPS	Merops MMP3_MOUSE -> FBLN2_MOUSE @259
MMP3_MOUSE	569	VSEM.\|.MEMA	inferred from experiment	unknown	MEROPS	Merops MMP3_MOUSE -> FBLN2_MOUSE @569

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)