P38606: V-type proton ATPase catalytic subunit A

General Information

Protein names	- V-type proton ATPase catalytic subunit A - V-ATPase subunit A - 7.1.2.2 - V-ATPase 69 kDa subunit - Vacuolar ATPase isoform VA68 - Vacuolar proton pump subunit alpha
Gene names	ATP6V1A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P38606

6 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDFSKLPKIL DEDKESTFGY VHGVSGPVVT ACDMAGAAMY ELVRVGHSEL VGEIIRLEGD
        70         80         90        100        110        120
MATIQVYEET SGVSVGDPVL RTGKPLSVEL GPGIMGAIFD GIQRPLSDIS SQTQSIYIPR
       130        140        150        160        170        180
GVNVSALSRD IKWDFTPCKN LRVGSHITGG DIYGIVSENS LIKHKIMLPP RNRGTVTYIA
       190        200        210        220        230        240
PPGNYDTSDV VLELEFEGVK EKFTMVQVWP VRQVRPVTEK LPANHPLLTG QRVLDALFPC
       250        260        270        280        290        300
VQGGTTAIPG AFGCGKTVIS QSLSKYSNSD VIIYVGCGER GNEMSEVLRD FPELTMEVDG
       310        320        330        340        350        360
KVESIMKRTA LVANTSNMPV AAREASIYTG ITLSEYFRDM GYHVSMMADS TSRWAEALRE
       370        380        390        400        410        420
ISGRLAEMPA DSGYPAYLGA RLASFYERAG RVKCLGNPER EGSVSIVGAV SPPGGDFSDP
       430        440        450        460        470        480
VTSATLGIVQ VFWGLDKKLA QRKHFPSVNW LISYSKYMRA LDEYYDKHFT EFVPLRTKAK
       490        500        510        520        530        540
EILQEEEDLA EIVQLVGKAS LAETDKITLE VAKLIKDDFL QQNGYTPYDR FCPFYKTVGM
       550        560        570        580        590        600
LSNMIAFYDM ARRAVETTAQ SDNKITWSII REHMGDILYK LSSMKFKDPL KDGEAKIKSD
       610
YAQLLEDMQN AFRSLED

Isoforms

- Isoform 2 of V-type proton ATPase catalytic subunit A

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P38606-1-acetylation	MDFSKL...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P38606-1-unknown	MDFSKL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P38606-34-unknown	MAGAAM...	34		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417545
P38606-34-unknown	MAGAAM...	34		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439874
P38606-70-	TSGVSV...	70			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P38606-309-	TALVAN...	309			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P38606-409-	AVSPPG...	409			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QVRPVT	217	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417545
...VTEKLP	221	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419294
...RSLED	617	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)