P39053: Dynamin-1

General Information

Protein names	- Dynamin-1 - 3.6.5.5
Gene names	Dnm1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P39053

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Dynamin-1 - Isoform 3 of Dynamin-1 - Isoform 4 of Dynamin-1 - Isoform 5 of Dynamin-1 - Isoform 6 of Dynamin-1

Sequence View

        10         20         30         40         50         60
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
        70         80         90        100        110        120
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI
       130        140        150        160        170        180
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD
       190        200        210        220        230        240
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK
       250        260        270        280        290        300
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL
       310        320        330        340        350        360
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA
       370        380        390        400        410        420
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI
       430        440        450        460        470        480
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID
       490        500        510        520        530        540
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE
       550        560        570        580        590        600
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY
       610        620        630        640        650        660
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE
       670        680        690        700        710        720
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE
       730        740        750        760        770        780
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT
       790        800        810        820        830        840
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP
       850        860
PGVPSLGAWR LNSPQGKHEN RAGKARL         10         20         30         40         50         60
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
        70         80         90        100        110        120
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI
       130        140        150        160        170        180
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD
       190        200        210        220        230        240
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK
       250        260        270        280        290        300
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL
       310        320        330        340        350        360
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA
       370        380        390        400        410        420
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI
       430        440        450        460        470        480
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID
       490        500        510        520        530        540
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE
       550        560        570        580        590        600
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY
       610        620        630        640        650        660
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE
       670        680        690        700        710        720
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE
       730        740        750        760        770        780
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT
       790        800        810        820        830        840
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP
       850        860
PGVPSLGAWR LNSPQGKHEN RAGKARL         10         20         30         40         50         60
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
        70         80         90        100        110        120
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI
       130        140        150        160        170        180
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD
       190        200        210        220        230        240
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK
       250        260        270        280        290        300
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL
       310        320        330        340        350        360
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA
       370        380        390        400        410        420
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI
       430        440        450        460        470        480
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID
       490        500        510        520        530        540
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE
       550        560        570        580        590        600
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY
       610        620        630        640        650        660
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE
       670        680        690        700        710        720
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE
       730        740        750        760        770        780
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT
       790        800        810        820        830        840
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP
       850        860
PGVPSLGAWR LNSPQGKHEN RAGKARL         10         20         30         40         50         60
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
        70         80         90        100        110        120
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI
       130        140        150        160        170        180
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD
       190        200        210        220        230        240
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK
       250        260        270        280        290        300
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL
       310        320        330        340        350        360
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA
       370        380        390        400        410        420
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI
       430        440        450        460        470        480
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID
       490        500        510        520        530        540
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE
       550        560        570        580        590        600
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY
       610        620        630        640        650        660
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE
       670        680        690        700        710        720
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE
       730        740        750        760        770        780
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT
       790        800        810        820        830        840
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP
       850        860
PGVPSLGAWR LNSPQGKHEN RAGKARL         10         20         30         40         50         60
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
        70         80         90        100        110        120
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI
       130        140        150        160        170        180
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD
       190        200        210        220        230        240
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK
       250        260        270        280        290        300
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL
       310        320        330        340        350        360
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA
       370        380        390        400        410        420
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI
       430        440        450        460        470        480
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID
       490        500        510        520        530        540
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE
       550        560        570        580        590        600
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY
       610        620        630        640        650        660
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE
       670        680        690        700        710        720
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE
       730        740        750        760        770        780
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT
       790        800        810        820        830        840
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP
       850        860
PGVPSLGAWR LNSPQGKHEN RAGKARL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P39053-1-unknown	MGNRGM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P39053-1-unknown	MGNRGM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73424
P39053-1-unknown	MGNRGM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73425
P39053-1-unknown	MGNRGM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73426
P39053-1-unknown	MGNRGM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73427
P39053-1-unknown	MGNRGM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73428
P39053-361-unknown	RINRIF...	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31410
P39053-361-unknown	RINRIF...	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151218
P39053-361-unknown	RINRIF...	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151219
P39053-361-unknown	RINRIF...	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151220
P39053-361-unknown	RINRIF...	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151221
P39053-361-unknown	RINRIF...	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151222

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LSGGAR	360	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31410
...LSGGAR	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134620
...LSGGAR	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134621
...LSGGAR	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134622
...LSGGAR	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134623
...LSGGAR	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134624
...GKARL	867	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_MOUSE	360	GGAR.\|.RINR	inferred from experiment	unknown	MEROPS	Reiser J	Sever S et al.:Proteolytic processing of dynam... (C01.032)	17671649,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)