P41236: Protein phosphatase inhibitor 2

General Information

Protein names	- Protein phosphatase inhibitor 2 - IPP-2
Gene names	PPP1R2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P41236

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASTASHRP IKGILKNKTS TTSSMVASAE QPRGNVDEEL SKKSQKWDEM NILATYHPAD
        70         80         90        100        110        120
KDYGLMKIDE PSTPYHSMMG DDEDACSDTE ATEAMAPDIL ARKLAAAEGL EPKYRIQEQE
       130        140        150        160        170        180
SSGEEDSDLS PEEREKKRQF EMKRKLHYNE GLNIKLARQL ISKDLHDDDE DEEMLETADG
       190        200
ESMNTEESNQ GSTPSDQQQN KLRSS

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P41236-2-unknown	MAASTA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P41236-2-Acetylation	AASTAS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P41236-24-	SMVASA...	24			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P41236-24-	SMVASA...	24			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P41236-24-	SMVASA...	24			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P41236-24-	SMVASA...	24			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P41236-24-	SMVASA...	24			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P41236-94-	AMAPDI...	94			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...STPSDQ	196	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000400238
	...KLRSS	205	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)