P45973: Chromobox protein homolog 5

General Information

Protein names	- Chromobox protein homolog 5 - Antigen p25 - Heterochromatin protein 1 homolog alpha - HP1 alpha
Gene names	CBX5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P45973

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKKTKRTAD SSSSEDEEEY VVEKVLDRRV VKGQVEYLLK WKGFSEEHNT WEPEKNLDCP
        70         80         90        100        110        120
ELISEFMKKY KKMKEGENNK PREKSESNKR KSNFSNSADD IKSKKKREQS NDIARGFERG
       130        140        150        160        170        180
LEPEKIIGAT DSCGDLMFLM KWKDTDEADL VLAKEANVKC PQIVIAFYEE RLTWHAYPED
       190
AENKEKETAK S

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P45973-1-unknown	MGKKTK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P45973-2-unknown	GKKTKR...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P45973-46-unknown	EEHNTW...	46	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5877
P45973-95-unknown	SNSADD...	95		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P45973-176-unknown	AYPEDA...	176	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5878

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...WKGFSE	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5877
...SNKRKS	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000450190
...RLTWHA	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5878
...ETAKS	191	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	45	GFSE.\|.EEHN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	175	TWHA.\|.AYPE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)