P47738: Aldehyde dehydrogenase, mitochondrial

General Information

Protein names	- Aldehyde dehydrogenase, mitochondrial - 1.2.1.3 - AHD-M1 - ALDH class 2 - ALDH-E2 - ALDHI
Gene names	Aldh2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P47738

5 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLRAALTTVR RGPRLSRLLS AAATSAVPAP NHQPEVFCNQ IFINNEWHDA VSRKTFPTVN
        70         80         90        100        110        120
PSTGEVICQV AEGNKEDVDK AVKAARAAFQ LGSPWRRMDA SDRGRLLYRL ADLIERDRTY
       130        140        150        160        170        180
LAALETLDNG KPYVISYLVD LDMVLKCLRY YAGWADKYHG KTIPIDGDFF SYTRHEPVGV
       190        200        210        220        230        240
CGQIIPWNFP LLMQAWKLGP ALATGNVVVM KVAEQTPLTA LYVANLIKEA GFPPGVVNIV
       250        260        270        280        290        300
PGFGPTAGAA IASHEGVDKV AFTGSTEVGH LIQVAAGSSN LKRVTLELGG KSPNIIMSDA
       310        320        330        340        350        360
DMDWAVEQAH FALFFNQGQC CCAGSRTFVQ ENVYDEFVER SVARAKSRVV GNPFDSRTEQ
       370        380        390        400        410        420
GPQVDETQFK KILGYIKSGQ QEGAKLLCGG GAAADRGYFI QPTVFGDVKD GMTIAKEEIF
       430        440        450        460        470        480
GPVMQILKFK TIEEVVGRAN DSKYGLAAAV FTKDLDKANY LSQALQAGTV WINCYDVFGA
       490        500        510
QSPFGGYKMS GSGRELGEYG LQAYTEVKTV TVKVPQKNS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P47738-19-unknown	LSAAAT...	19		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34643
P47738-20-Acetylation	SAAATS...	20	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47738-20-Acetylation	SAAATS...	20	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P47738-69-unknown	QVAEGN...	69		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29972
P47738-70-unknown	VAEGNK...	70		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29973
P47738-70-unknown	VAEGNK...	70		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28883
P47738-272-unknown	IQVAAG...	272		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29974

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLSRLL	18	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34643
...GEVICQ	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29972
...EVICQV	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29973
...EVICQV	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28883
...GQIIPW	186	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123545
...EVGHLI	271	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29974
...PQKNS	519	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MPPB_MOUSE	18	SRLL.\|.LSAA	inferred from experiment	unknown	MEROPS	Ito A	Kitada S et al.:A protein from a parasitic micr... (M16.003)	17158683,
CATE_MOUSE	68	VICQ.\|.QVAE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDH2_MOUSE @68
CATE_MOUSE	69	ICQV.\|.VAEG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDH2_MOUSE @69
CATD_MOUSE	69	ICQV.\|.VAEG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ALDH2_MOUSE @69
CATE_MOUSE	271	GHLI.\|.IQVA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDH2_MOUSE @271

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)