P47895: Aldehyde dehydrogenase family 1 member A3

General Information

Protein names	- Aldehyde dehydrogenase family 1 member A3 - 1.2.1.36 {ECO:0000269\|PubMed:27759097} - Aldehyde dehydrogenase 6 - Retinaldehyde dehydrogenase 3 - RALDH-3 - RalDH3
Gene names	ALDH1A3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P47895

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATANGAVEN GQPDRKPPAL PRPIRNLEVK FTKIFINNEW HESKSGKKFA TCNPSTREQI
        70         80         90        100        110        120
CEVEEGDKPD VDKAVEAAQV AFQRGSPWRR LDALSRGRLL HQLADLVERD RATLAALETM
       130        140        150        160        170        180
DTGKPFLHAF FIDLEGCIRT LRYFAGWADK IQGKTIPTDD NVVCFTRHEP IGVCGAITPW
       190        200        210        220        230        240
NFPLLMLVWK LAPALCCGNT MVLKPAEQTP LTALYLGSLI KEAGFPPGVV NIVPGFGPTV
       250        260        270        280        290        300
GAAISSHPQI NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGKNPCIVC ADADLDLAVE
       310        320        330        340        350        360
CAHQGVFFNQ GQCCTAASRV FVEEQVYSEF VRRSVEYAKK RPVGDPFDVK TEQGPQIDQK
       370        380        390        400        410        420
QFDKILELIE SGKKEGAKLE CGGSAMEDKG LFIKPTVFSE VTDNMRIAKE EIFGPVQPIL
       430        440        450        460        470        480
KFKSIEEVIK RANSTDYGLT AAVFTKNLDK ALKLASALES GTVWINCYNA LYAQAPFGGF
       490        500        510
KMSGNGRELG EYALAEYTEV KTVTIKLGDK NP

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P47895-2-unknown	MATANG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47895-2-Acetylation	ATANGA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47895-2-Acetylation	ATANGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P47895-67-unknown	DKPDVD...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19127

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EVEEGD	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19127
...HEPIGV	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452789
...GDKNP	512	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	66	EEGD.\|.DKPD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)