P48556: 26S proteasome non-ATPase regulatory subunit 8

General Information

Protein names	- 26S proteasome non-ATPase regulatory subunit 8 - 26S proteasome regulatory subunit RPN12 - 26S proteasome regulatory subunit S14 - p31
Gene names	PSMD8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P48556

5 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFIKGRAPRA PPRERRRATR GGLRQVVAPP RALGSTSRPH FRRASVCRRR CRKSGGLLAA
        70         80         90        100        110        120
SRKMAAAAVN GAAGFSSSGP AATSGAVLQA ATGMYEQLKG EWNRKSPNLS KCGEELGRLK
       130        140        150        160        170        180
LVLLELNFLP TTGTKLTKQQ LILARDILEI GAQWSILRKD IPSFERYMAQ LKCYYFDYKE
       190        200        210        220        230        240
QLPESAYMHQ LLGLNLLFLL SQNRVAEFHT ELERLPAKDI QTNVYIKHPV SLEQYLMEGS
       250        260        270        280        290        300
YNKVFLAKGN IPAESYTFFI DILLDTIRDE IAGCIEKAYE KILFTEATRI LFFNTPKKMT
       310        320        330        340        350
DYAKKRGWVL GPNNYYSFAS QQQKPEDTTI PSTELAKQVI EYARQLEMIV

Isoforms

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P48556-1-unknown	MFIKGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P48556-53-unknown	KSGGLL...	53	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467146
P48556-64-unknown	MAAAAV...	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473312
P48556-64-unknown	MAAAAV...	64	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P48556-168-unknown	MAQLKC...	168	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465107
P48556-168-unknown	MAQLKC...	168	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468445
P48556-320-unknown	SQQQKP...	320	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5894

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VSLEQY	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468445
...YYSFAS	319	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5894
...LEMIV	350	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	319	SFAS.\|.SQQQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)