P49312: Heterogeneous nuclear ribonucleoprotein A1

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein A1 - hnRNP A1 - HDP-1 - Helix-destabilizing protein - Single-strand-binding protein - Topoisomerase-inhibitor suppressed - hnRNP core protein A1 - Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Gene names	Hnrnpa1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P49312

7 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN TKRSRGFGFV
        70         80         90        100        110        120
TYATVEEVDA AMNARPHKVD GRVVEPKRAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH
       130        140        150        160        170        180
LRDYFEQYGK IEVIEIMTDR GSGKKRGFAF VTFDDHDSVD KIVIQKYHTV NGHNCEVRKA
       190        200        210        220        230        240
LSKQEMASAS SSQRGRSGSG NFGGGRGGGF GGNDNFGRGG NFSGRGGFGG SRGGGGYGGS
       250        260        270        280        290        300
GDGYNGFGND GSNFGGGGSY NDFGNYNNQS SNFGPMKGGN FGGRSSGPYG GGGQYFAKPR
       310        320
NQGGYGGSSS SSSYGSGRRF

Isoforms

- Isoform Short of Heterogeneous nuclear ribonucleoprotein A1

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P49312-1-Acetylation	MSKSES...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P49312-1-Acetylation	MSKSES...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96349
P49312-1-unknown	MSKSES...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88050
P49312-2-Acetylation	SKSESP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P49312-2-Acetylation	SKSESP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P49312-2-Acetylation	SKSESP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110097
P49312-21-unknown	LSFETT...	21		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33588
P49312-21-unknown	LSFETT...	21		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136907
P49312-60-unknown	VTYATV...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30009
P49312-60-unknown	VTYATV...	60		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139894
P49312-63-unknown	ATVEEV...	63		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30011
P49312-63-unknown	ATVEEV...	63		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140166
P49312-65-unknown	VEEVDA...	65		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30013
P49312-65-unknown	VEEVDA...	65		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140280

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LFIGGL	20	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33588
...RGFGFV	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30009
...RGFGFV	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122999
...GFVTYA	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30011
...GFVTYA	62	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123276
...VTYATV	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30013
...VTYATV	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123402
...SGRRF	320	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
MMP2_MOUSE	20	IGGL.\|.LSFE	inferred from experiment	unknown	MEROPS	Merops MMP2_MOUSE -> ROA1_MOUSE @20
CATE_MOUSE	59	FGFV.\|.VTYA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ROA1_MOUSE @59
CATE_MOUSE	62	VTYA.\|.ATVE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ROA1_MOUSE @62
CATE_MOUSE	64	YATV.\|.VEEV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ROA1_MOUSE @64

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)