P49755: Transmembrane emp24 domain-containing protein 10

General Information

Protein names	- Transmembrane emp24 domain-containing protein 10 - 21 kDa transmembrane-trafficking protein - S31III125 - S31I125 - Tmp-21-I - Transmembrane protein Tmp21 - p23 - p24 family protein delta-1 - p24delta1 - p24delta
Gene names	TMED10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P49755

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGLSGPPAR RGPFPLALLL LFLLGPRLVL AISFHLPINS RKCLREEIHK DLLVTGAYEI
        70         80         90        100        110        120
SDQSGGAGGL RSHLKITDSA GHILYSKEDA TKGKFAFTTE DYDMFEVCFE SKGTGRIPDQ
       130        140        150        160        170        180
LVILDMKHGV EAKNYEEIAK VEKLKPLEVE LRRLEDLSES IVNDFAYMKK REEEMRDTNE
       190        200        210
STNTRVLYFS IFSMFCLIGL ATWQVFYLRR FFKAKKLIE

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P49755-32-	ISFHLP...	32		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P49755-32-unknown	ISFHLP...	32	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49755-32-unknown	ISFHLP...	32		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KKLIE	219	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)