P49767: Vascular endothelial growth factor C
| Protein names | - Vascular endothelial growth factor C - VEGF-C - Flt4 ligand - Flt4-L - Vascular endothelial growth factor-related protein - VRP |
|---|---|
| Gene names | VEGFC |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P49767 |
3
N-termini
2
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MHLLGFFSVA CSLLAAALLP GPREAPAAAA AFESGLDLSD AEPDAGEATA YASKDLEEQL
70 80 90 100 110 120
RSVSSVDELM TVLYPEYWKM YKCQLRKGGW QHNREQANLN SRTEETIKFA AAHYNTEILK
130 140 150 160 170 180
SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY
190 200 210 220 230 240
LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRRSLP ATLPQCQAAN
250 260 270 280 290 300
KTCPTNYMWN NHICRCLAQE DFMFSSDAGD DSTDGFHDIC GPNKELDEET CQCVCRAGLR
310 320 330 340 350 360
PASCGPHKEL DRNSCQCVCK NKLFPSQCGA NREFDENTCQ CVCKRTCPRN QPLNPGKCAC
370 380 390 400 410
ECTESPQKCL LKGKKFHHQT CSCYRRPCTN RQKACEPGFS YSEEVCRCVP SYWKRPQMS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 4 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P49767-103-unknown | TEETIK... | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16352 | |||
| P49767-112-unknown | AHYNTE... | 112 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P49767-228-unknown | SLPATL... | 228 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9768 | |||
| P49767-228-unknown | SLPATL... | 228 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27043 | |||
| P49767-228-unknown | SLPATL... | 228 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27340 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...NLNSRT | 102 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16352 | |||
| ...SIIRRS | 227 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...SIIRRS | 227 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9768 | |||
| ...SIIRRS | 227 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27043 | |||
| ...SIIRRS | 227 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27340 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| KLK4_HUMAN | 102 | NSRT.|.TEET | inferred from experiment | unknown | MEROPS | Nelson PS | Matsumura M et al.:Substrates of the prostate-spec... (S01.251) | 15389820, |
| FURIN_HUMAN | 227 | IRRS.|.SLPA | inferred from experiment | unknown | MEROPS | Khatib AM | Siegfried G et al.:The secretory proprotein conver... (S08.071) | 12782675, |
| PCSK5_HUMAN | 227 | IRRS.|.SLPA | inferred from experiment | unknown | MEROPS | Khatib AM | Siegfried G et al.:The secretory proprotein conver... (S08.071) | 12782675, |
| PCSK7_HUMAN | 227 | IRRS.|.SLPA | inferred from experiment | unknown | MEROPS | Khatib AM | Siegfried G et al.:The secretory proprotein conver... (S08.071) | 12782675, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|