TopFIND 4.0

P51512: Matrix metalloproteinase-16

General Information

Protein names
- Matrix metalloproteinase-16
- MMP-16
- 3.4.24.-
- MMP-X2
- Membrane-type matrix metalloproteinase 3
- MT-MMP 3
- MTMMP3
- Membrane-type-3 matrix metalloproteinase
- MT3-MMP
- MT3MMP
Gene names MMP16
Organism Homo sapiens
Protease Family M10.016
Protease ID M10.016
Chromosome location
UniProt ID P51512

4

N-termini

2

C-termini

1

Cleavages

43

Substrates

Sequence

        10         20         30         40         50         60 
MILLTFSTGR RLDFVHHSGV FFLQTLLWIL CATVCGTEQY FNVEVWLQKY GYLPPTDPRM 
        70         80         90        100        110        120 
SVLRSAETMQ SALAAMQQFY GINMTGKVDR NTIDWMKKPR CGVPDQTRGS SKFHIRRKRY 
       130        140        150        160        170        180 
ALTGQKWQHK HITYSIKNVT PKVGDPETRK AIRRAFDVWQ NVTPLTFEEV PYSELENGKR 
       190        200        210        220        230        240 
DVDITIIFAS GFHGDSSPFD GEGGFLAHAY FPGPGIGGDT HFDSDEPWTL GNPNHDGNDL 
       250        260        270        280        290        300 
FLVAVHELGH ALGLEHSNDP TAIMAPFYQY METDNFKLPN DDLQGIQKIY GPPDKIPPPT 
       310        320        330        340        350        360 
RPLPTVPPHR SIPPADPRKN DRPKPPRPPT GRPSYPGAKP NICDGNFNTL AILRREMFVF 
       370        380        390        400        410        420 
KDQWFWRVRN NRVMDGYPMQ ITYFWRGLPP SIDAVYENSD GNFVFFKGNK YWVFKDTTLQ 
       430        440        450        460        470        480 
PGYPHDLITL GSGIPPHGID SAIWWEDVGK TYFFKGDRYW RYSEEMKTMD PGYPKPITVW 
       490        500        510        520        530        540 
KGIPESPQGA FVHKENGFTY FYKGKEYWKF NNQILKVEPG YPRSILKDFM GCDGPTDRVK 
       550        560        570        580        590        600 
EGHSPPDDVD IVIKLDNTAS TVKAIAIVIP CILALCLLVL VYTVFQFKRK GTPRHILYCK 
   
RSMQEWV

Isoforms

- Isoform Short of Matrix metalloproteinase-16

Sequence View

        10         20         30         40         50         60 
MILLTFSTGR RLDFVHHSGV FFLQTLLWIL CATVCGTEQY FNVEVWLQKY GYLPPTDPRM 
        70         80         90        100        110        120 
SVLRSAETMQ SALAAMQQFY GINMTGKVDR NTIDWMKKPR CGVPDQTRGS SKFHIRRKRY 
       130        140        150        160        170        180 
ALTGQKWQHK HITYSIKNVT PKVGDPETRK AIRRAFDVWQ NVTPLTFEEV PYSELENGKR 
       190        200        210        220        230        240 
DVDITIIFAS GFHGDSSPFD GEGGFLAHAY FPGPGIGGDT HFDSDEPWTL GNPNHDGNDL 
       250        260        270        280        290        300 
FLVAVHELGH ALGLEHSNDP TAIMAPFYQY METDNFKLPN DDLQGIQKIY GPPDKIPPPT 
       310        320        330        340        350        360 
RPLPTVPPHR SIPPADPRKN DRPKPPRPPT GRPSYPGAKP NICDGNFNTL AILRREMFVF 
       370        380        390        400        410        420 
KDQWFWRVRN NRVMDGYPMQ ITYFWRGLPP SIDAVYENSD GNFVFFKGNK YWVFKDTTLQ 
       430        440        450        460        470        480 
PGYPHDLITL GSGIPPHGID SAIWWEDVGK TYFFKGDRYW RYSEEMKTMD PGYPKPITVW 
       490        500        510        520        530        540 
KGIPESPQGA FVHKENGFTY FYKGKEYWKF NNQILKVEPG YPRSILKDFM GCDGPTDRVK 
       550        560        570        580        590        600 
EGHSPPDDVD IVIKLDNTAS TVKAIAIVIP CILALCLLVL VYTVFQFKRK GTPRHILYCK 
   
RSMQEWV



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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 43 Substrates

N-termini

C-termini

Cleavages

Substrates