P54775: 26S proteasome regulatory subunit 6B

General Information

Protein names	- 26S proteasome regulatory subunit 6B - 26S proteasome AAA-ATPase subunit RPT3 - CIP21 - MB67-interacting protein - MIP224 - Proteasome 26S subunit ATPase 4 - Tat-binding protein 7 - TBP-7
Gene names	Psmc4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P54775

8 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEEIGILVEK IQDEIPALSV SRPQTGLSFL GPEPEDLEDL YSRYKKLQQE LEFLEVQEEY
        70         80         90        100        110        120
IKDEQKNLKK EFLHAQEEVK RIQSIPLVIG QFLEAVDQNT AIVGSTTGSN YYVRILSTID
       130        140        150        160        170        180
RELLKPNASV ALHKHSNALV DVLPPEADSS IMMLTSDQKP DVMYADIGGM DIQKQEVREA
       190        200        210        220        230        240
VELPLTHFEL YKQIGIDPPR GVLMYGPPGC GKTMLAKAVA HHTTAAFIRV VGSEFVQKYL
       250        260        270        280        290        300
GEGPRMVRDV FRLAKENAPA IIFIDEIDAI ATKRFDAQTG ADREVQRILL ELLNQMDGFD
       310        320        330        340        350        360
QNVNVKVIMA TNRADTLDPA LLRPGRLDRK IEFPLPDRRQ KRLIFSTITS KMNLSEEVDL
       370        380        390        400        410
EDYVARPDKI SGADINSICQ ESGMLAVREN RYIVLAKDFE KAYKTVIKKD EQEHEFYK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P54775-1-Acetylation	MEEIGI...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P54775-14-unknown	EIPALS...	14		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P54775-30-unknown	LGPEPE...	30		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30097
P54775-164-unknown	YADIGG...	164		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30098
P54775-166-unknown	DIGGMD...	166			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P54775-191-unknown	YKQIGI...	191		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30099
P54775-253-unmodified	LAKENA...	253			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P54775-330-unmodified	KIEFPL...	330			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TGLSFL	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30097
...KPDVMY	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30098
...THFELY	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30099
...HEFYK	418	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	29	LSFL.\|.LGPE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PRS6B_MOUSE @29
CATE_MOUSE	163	DVMY.\|.YADI	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PRS6B_MOUSE @163
CATE_MOUSE	190	FELY.\|.YKQI	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PRS6B_MOUSE @190

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)