P54822: Adenylosuccinate lyase

General Information

Protein names	- Adenylosuccinate lyase - ASL - 4.3.2.2 {ECO:0000250\|UniProtKB:P30566} - Adenylosuccinase - ASase
Gene names	Adsl
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P54822

4 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASGDPGSA ESYRSPLAAR YASREMCFLF SDRYKFQTWR QLWLWLAEAE QTLGLPITDE
        70         80         90        100        110        120
QIQEMKSNLN NIDFQMAAEE EKRLRHDVMA HVHTFGHCCP KAAGIIHLGA TSCYVGDNTD
       130        140        150        160        170        180
LIILRNAFDL LLPKLARVIS RLADFAKDRA DLPTLGFTHF QPAQLTTVGK RCCLWIQDLC
       190        200        210        220        230        240
MDLQNLKRVR DELRFRGVKG TTGTQASFLQ LFEGDHQKVE QLDKMVTEKA GFKRAFIITG
       250        260        270        280        290        300
QTYTRKVDIE VLSVLASLGA SVHKICTDIR LLANLKEMEE PFEKQQIGSS AMPYKRNPMR
       310        320        330        340        350        360
SERCCSLARH LMALTMDPLQ TASVQWFERT LDDSANRRIC LAEAFLTADT ILNTLQNISE
       370        380        390        400        410        420
GLVVYPKVIE RRIRQELPFM ATENIIMAMV KAGGSRQDCH EKIRVLSQQA AAVVKQEGGD
       430        440        450        460        470        480
NDLIERIRAD AYFSPIHSQL EHLLDPSSFT GRAPQQVHRF LEEEVRPLLK PYGNEMAVKA

ELCL

Isoforms

Sequence View

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P54822-2-unknown	MAASGD...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P54822-2-unknown	MAASGD...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P54822-2-Acetylation	AASGDP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P54822-2-Acetylation	AASGDP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P54822-388-unknown	AMVKAG...	388		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30100
P54822-413-unknown	VVKQEG...	413		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33624

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AAEEEK	81	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000132524
...ENIIMA	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30100
...QQAAAV	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33624
...AELCL	484	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	387	IIMA.\|.AMVK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PUR8_MOUSE @387
MMP2_MOUSE	412	AAAV.\|.VVKQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)