P56959: RNA-binding protein FUS

General Information

Protein names	- RNA-binding protein FUS - Protein pigpen
Gene names	Fus
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P56959

2 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YGQSADTSGY GQSSYGSSYG
        70         80         90        100        110        120
QTQNTGYGTQ SAPQGYGSTG GYGSSQSSQS SYGQQSSYPG YGQQPAPSST SGSYGGSSQS
       130        140        150        160        170        180
SSYGQPQSGG YGQQSGYGGQ QQSYGQQQSS YNPPQGYGQQ NQYNSSSGGG GGGGGGNYGQ
       190        200        210        220        230        240
DQSSMSGGGG GGGYGNQDQS GGGGGGYGGG QQDRGGRGRG GGGGYNRSSG GYEPRGRGGG
       250        260        270        280        290        300
RGGRGGMGGS DRGGFNKFGG PRDQGSRHDS EQDNSDNNTI FVQGLGENVT IESVADYFKQ
       310        320        330        340        350        360
IGIIKTNKKT GQPMINLYTD RETGKLKGEA TVSFDDPPSA KAAIDWFDGK EFSGNPIKVS
       370        380        390        400        410        420
FATRRADFNR GGGNGRGGRG RGGPMGRGGY GGGGSGGGGR GGFPSGGGGG GGQQRAGDWK
       430        440        450        460        470        480
CPNPTCENMN FSWRNECNQC KAPKPDGPGG GPGGSHMGGN YGDDRRGRGG YDRGGYRGRG
       490        500        510
GDRGGFRGGR GGGDRGGFGP GKMDSRGEHR QDRRERPY

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P56959-1-unknown	MASNDY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P56959-419-unknown	WKCPNP...	419		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33635

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QRAGDW	418	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33635
...RGRGGY	470	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000133820
...KMDSRG	506	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134447
...RERPY	518	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	418	AGDW.\|.WKCP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)