TopFIND 4.0

P60896: 26S proteasome complex subunit SEM1

General Information

Protein names	- 26S proteasome complex subunit SEM1 - 26S proteasome complex subunit DSS1 - Deleted in split hand/split foot protein 1 - Split hand/foot deleted protein 1 - Split hand/foot malformation type 1 protein
Gene names	SHFM1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P60896

2

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MSEKKQPVDL GLLEEDDEFE EFPAEDWAGL DEDEDAHVWE DNWDDDNVED DFSNQLRAEL
70
EKHGYKMETS

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P60896-1-unknown	MSEKKQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P60896-47-unknown	NVEDDF...	47		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3221

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NWDDDN	46	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3221
	...KMETS	70	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...KMETS	70		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...KMETS	70		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASPE_HUMAN	46	DDDN.\|.NVED	inferred from experiment	unknown	MEROPS		Merops CASPE_HUMAN -> DSS1_HUMAN @46

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)