P31944: Caspase-14
Protein names | - Caspase-14 - CASP-14 - 3.4.22.- - Caspase-14 subunit p17, mature form - Caspase-14 subunit p10, mature form - Caspase-14 subunit p20, intermediate form - Caspase-14 subunit p8, intermediate form |
---|---|
Gene names | CASP14 |
Organism | Homo sapiens |
Protease Family | C14.018 |
Protease ID | C14.018 |
Chromosome location | |
UniProt ID | P31944 |
2
N-termini
2
C-termini
0
Cleavages
19
Substrates
Sequence
10 20 30 40 50 60
MSNPRSLEEE KYDMSGARLA LILCVTKARE GSEEDLDALE HMFRQLRFES TMKRDPTAEQ
70 80 90 100 110 120
FQEELEKFQQ AIDSREDPVS CAFVVLMAHG REGFLKGEDG EMVKLENLFE ALNNKNCQAL
130 140 150 160 170 180
RAKPKVYIIQ ACRGEQRDPG ETVGGDEIVM VIKDSPQTIP TYTDALHVYS TVEGYIAYRH
190 200 210 220 230 240
DQKGSCFIQT LVDVFTKRKG HILELLTEVT RRMAEAELVQ EGKARKTNPE IQSTLRKRLY
LQ
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 19 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P31944-0-unknown | QMSNPR... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P31944-153-unknown | KDSPQT... | 153 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...IVMVIK | 152 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...RLYLQ | 242 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
DDX21_HUMAN | 8 | RSDA.|.AGLE | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> DDX21_HUMAN @8 | ||
TOP1_HUMAN | 9 | HNDS.|.SQIE | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> TOP1_HUMAN @9 | ||
EIF3J_HUMAN | 17 | DADA.|.AFSV | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> EIF3J_HUMAN @17 | ||
EIF3J-Isoform3_HUMAN | 17 | DADA.|.AFSV | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3214 | ||
EIF3J-Isoform2_HUMAN | 17 | DADA.|.AFSV | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3214 | ||
ENPL_HUMAN | 28 | DVDG.|.GTVE | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> ENPL_HUMAN @28 | ||
SEM1_HUMAN | 46 | DDDN.|.NVED | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> DSS1_HUMAN @46 | ||
ZC3H4_HUMAN | 67 | EDDG.|.GAEE | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> ZC3H4_HUMAN @67 | ||
TR150_HUMAN | 391 | KSDS.|.SFAP | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> TR150_HUMAN @391 | ||
IF4B_HUMAN | 531 | KVDG.|.GMNA | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> IF4B_HUMAN @531 | ||
H90B3_HUMAN | 579 | VPDE.|.EIPP | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> H90B3_HUMAN @579 | ||
LRRF1-Isoform3_HUMAN | 617 | LADG.|.GDTL | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3222 | ||
LRRF1-Isoform2_HUMAN | 649 | LADG.|.GDTL | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3222 | ||
LRRF1_HUMAN | 673 | LADG.|.GDTL | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> LRRF1_HUMAN @673 | ||
HS90B_HUMAN | 706 | VPDE.|.EIPP | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> HS90B_HUMAN @706 | ||
BCLF1-Isoform4_HUMAN | 722 | QGDG.|.GIVE | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3227 | ||
BCLF1-Isoform3_HUMAN | 844 | QGDG.|.GIVE | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3227 | ||
BCLF1-Isoform2_HUMAN | 893 | QGDG.|.GIVE | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC3227 | ||
BCLF1_HUMAN | 895 | QGDG.|.GIVE | inferred from experiment | unknown | MEROPS | Merops CASPE_HUMAN -> BCLF1_HUMAN @895 |