TopFIND 4.0

P62310: U6 snRNA-associated Sm-like protein LSm3

General Information

Protein names	- U6 snRNA-associated Sm-like protein LSm3
Gene names	LSM3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62310

5

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MADDVDQQQT TNTVEEPLDL IRLSLDERIY VKMRNDRELR GRLHAYDQHL NMILGDVEET
70 80 90 100
VTTIEIDEET YEEIYKSTKR NIPMLFVRGD GVVLVAPPLR VG

Isoforms

Sequence View

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Biological System:

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62310-2-unknown	MADDVD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62310-2-Acetylation	ADDVDQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62310-2-Acetylation	ADDVDQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62310-2-Acetylation	ADDVDQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62310-7-	QQQTTN...	7			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P62310-7-	QQQTTN...	7			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P62310-7-unknown	QQQTTN...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1970
P62310-13-	TVEEPL...	13			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ADDVDQ	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1970
	...PLRVG	102	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	6	DVDQ.\|.QQQT	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> LSM3_HUMAN @6

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)