P62714: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform - PP2A-beta - 3.1.3.16
Gene names	PPP2CB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62714

4 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDDKAFTKEL DQWVEQLNEC KQLNENQVRT LCEKAKEILT KESNVQEVRC PVTVCGDVHG
        70         80         90        100        110        120
QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES
       130        140        150        160        170        180
RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI
       190        200        210        220        230        240
RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA
       250        260        270        280        290        300
HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV

TRRTPDYFL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P62714-1-unknown	MDDKAF...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P62714-66-unknown	MELFRI...	66	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428866
P62714-163-unknown	IFCLHG...	163	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430758
P62714-168-unknown	GGLSPS...	168	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6124
P62714-168-unknown	GGLSPS...	168	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P62714-168-unknown	GGLSPS...	168	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SNVQEV	47	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428142
...IFCLHG	167	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6124
...LQEVPH	190	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428866
...TFNHAN	231	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428618
...PDYFL methylation-	309	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	167	CLHG.\|.GGLS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)