P67936: Tropomyosin alpha-4 chain

General Information

Protein names	- Tropomyosin alpha-4 chain - TM30p1 - Tropomyosin-4
Gene names	TPM4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P67936

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE
        70         80         90        100        110        120
EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE
       130        140        150        160        170        180
EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE
       190        200        210        220        230        240
KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ

TLNELNCI

Isoforms

- Isoform 2 of Tropomyosin alpha-4 chain

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P67936-2-unknown	MAGLNS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P67936-2-Acetylation	AGLNSL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P67936-2-Acetylation	AGLNSL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P67936-2-Acetylation	AGLNSL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P67936-72-unknown	TALQKL...	72		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19285
P67936-72-unknown	TALQKL...	72		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142812

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QERLAT	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19285
...QERLAT	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126018
...ELNCI	248	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ELNCI	248	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88494

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	71	RLAT.\|.TALQ	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)